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Adherex Technologies, Inc.

Regulatory clearance granted for phase II trial of ADH-1 in Canada

Published in Lab Business Week, April 24th, 2005

Adherex Technologies, Inc., (ADH, AHX) announced that Health Canada has given regulatory clearance for the company's phase II Clinical Trial Application (CTA) for ADH-1, the company's lead anti-tumor biotechnology compound, also known as Exherin.

The phase II trial, which is expected to involve up to three cancer centers in Canada, will investigate repeated doses of ADH-1 in an every 3-week dosing schedule in patients whose tumors express the molecular target N-cadherin.

Specifically, the company will study eight different tumor types, including some more common ones such as breast and lung, as well as some rarer cancers such as adrenocortical and...

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