Russian Academy of Sciences, Moscow
Chimeric constructs generate recombinant IgE antibody upon transfection
Published in Lab Business Week, April 24th, 2005
"Transient expression of recombinant gene constructs is now more widely used in gene therapy as well as in DNA vaccination. In this study, the ability of one and the same genetic construct to drive gene expression both in cell culture and in tissues of the whole organism was demonstrated. Chinese hamster ovarian cells (CHO) were transfected in vitro with plasmids bearing the genes for chimeric IgE (mouse/human) antibodies under control of the human cytomegalovirus (hCMV) promoter," scientists in Russia report.
"Secretion of recombinant IgE antibodies by transfected cells reached...
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Source: Lab Business Week (2005-04-24)
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