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University College, London

Lack of uniform method complicates comparisons of endothelial dysfunction

Published in Lab Business Week, May 1st, 2005

A recent report provides a review of methods currently used for assessment of in vivo endothelial function.

According to the review from England, "An intact vascular endothelium is critical to the maintenance of normal arterial tone and coagulation status. Endothelial injury leading to dysfunction is thought to be a precursor to most if not all vascular disease, and has been implicated as a critical event in atherosclerosis. At present there are several methods available for detection of in vivo endothelial function, and the aim of [our] study was to critically review these methods."

T.A. Alam and colleagues of University College in London continued,...

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