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Uppsala University, Sweden

Faulty folding of protein in the environment may cause disease

Published in Lab Business Week, May 8th, 2005

Serious diseases have been shown to be related to unhealthy protein chains that occur when proteins fold "incorrectly."

In an article in the scientific journal Proceedings of the National Academy of Science a research team from Uppsala University has shown that similar protein chains in our environment may hasten the process.

Under certain conditions, incorrectly folded proteins can transmit diseases from one individual to another. This is the mechanism in diseases caused by prions, such as mad cow disease or Creutzfeldt-Jakob disease. In principle prions are normal proteins, but they have an abnormal three-dimensional structure. Prions bring...

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