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Univ. California Irvine

Researchers have method for predicting best use of cancer-fighting drugs

Published in Lab Business Week, July 17th, 2005

University of California Irvine researchers have developed a method that can help doctors choose the best combination of drugs for fighting cancer - a development that may lead to more effective treatment strategies.

The method is based on a mathematical model that determines when a cancer becomes drug-resistant during therapy. It does this by estimating the probability of finding drug-resistant mutant cells at different stages of cancer progression and examining the fate of individual mutant colonies during therapy. It then pinpoints under what circumstances these mutant cells become a problem and the therapy stops being effective. The finding will help physicians...

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