Published in Lab Business Week, July 17th, 2005
Scientists in Europe, from whom the technology was licensed by Duska, have demonstrated in an animal glaucoma model in vivo that increased intraocular pressure leads to the release of adenosine 5'-triphosphate (ATP) into the extracellular space in the eye, upregulation of the P2X7 receptor (P2X7R), and its activation by ATP. The activation of the P2X7R is known to open cell membrane pores, through which large molecules can enter and damage the...
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