Targeted Genetics Corp.
Gene-focused company announces patent issuance to make adeno-associated virus
Published in Lab Business Week, September 4th, 2005
The patent, U.S. No. 6,924,128, is titled "Methods and Cell Line Useful for Production of Recombinant Adeno-Associated Viruses" and covers the production of AAV vectors using cell lines that have necessary AAV functions turned on during the manufacturing process.
Production of AAV vectors requires the introduction of several elements into a cell, including the AAV vector and gene of interest, AAV rep and cap genes and genes provided from a helper virus. However, rep proteins can be toxic to some...
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Source: Lab Business Week (2005-09-04)
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