Published in Lab Business Week, December 25th, 2005
"Mitochondrial uncoupling proteins only catalyze proton transport when they are activated. Activators include superoxide and reactive alkenals, suggesting new physiological functions for UCP2 and UCP3: their activation by superoxide when protonmotive force is high causes mild uncoupling, which lowers protonmotive force and attenuates superoxide generation by the electron transport chain," scientists writing in the journal...
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