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Cambridge Institute for Medical Research

Studies of obese children reveal body-weight control hormone

Published in Lab Business Week, March 12th, 2006

Two new studies of obese children reveal that a single change in a particular brain hormone can increase a person's risk of obesity.

Researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight.

The findings, published in the February 8, 2006, issue of Cell Metabolism, implicate the hormone in the maintenance of normal body weight and suggest that drugs that mimic the chemical might offer a new avenue for obesity treatment.

The studies' lead authors are Stephen O'Rahilly, of the Cambridge Institute for Medical...

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