Albert Einstein College of Medicine, New Hyde Park
C-reactive protein modulates nitric oxide and superoxide in rat mesangial cells
Published in Lab Business Week, July 2nd, 2006
According to a study from the United States, "C-reactive protein (CRP) has been linked to cardiovascular and renal disease. We evaluated the effects of CRP on the production of nitric oxide (NO) and superoxide by rat mesangial cells (RMC) and the impact on cell function."
"RMC were incubated with cytokines (IFN-gamma, IL-1beta, and LPS) and CRP (10-100 mcg/ml) for 24-72 h," wrote H. Trachtman and colleagues at Albert Einstein College of Medicine in New Hyde Park. "Exposure to CRP resulted in a time- and dose-dependent reduction in NO accumulation (p<0.05). Although...
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Source: Lab Business Week (2006-07-02)
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