Universita di Roma La Sapienza, Italy

Researchers from Italy and the United States report details of new studies and findings in the area of HIV/AIDS

Published in Lab Business Week, July 16th, 2006

HIV/AIDS data are the focus of recent research from Italy and the United States.

Study 1: Bifunctional quinolonyl diketo acid derivatives inhibit HIV-1 integrase.

According to recent research published in the Journal of Medicinal Chemistry, "The virally encoded integrase protein is an essential enzyme in the life cycle of the HIV-1 virus and represents an attractive and validated tar get in the development of therapeutics against HIV infection.

"Drugs that selectively inhibit this enzyme, when used in combination with inhibitors of reverse transcriptase and protease, are believed to be highly effective in suppressing the...

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Source: Lab Business Week (2006-07-16)

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