Hopital Foch, Suresnes, France

Colorectal cancer response to FOLFIRI-3 treatment evaluated

Published in Lab Business Week, July 16th, 2006

Treating colorectal cancer with FOLFIRI-3 (double infusion of irinotecan combined with leucovorin 5-fluorouracil [LV5FU]) after FOLFOX proves to be promising.

According to recent research published in the British Journal of Cancer, "In advanced colorectal cancer previously treated with oxaliplatin, efficacy of irinotecan-based chemotherapy is poor and the best regimen is not defined. We designed FOLFIRI-3 and conducted a phase II study to establish its efficacy and safety in advanced colorectal cancer patients previously treated with FOLFOX."

"FOLFIRI-3 consisted of irinotecan 100 mg/m² as a 60-min infusion on day 1, running...

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Source: Lab Business Week (2006-07-16)

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