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Breast Cancer

Lawrence Berkeley reports tissue geometry plays crucial role in breast cell invasion

Published in Lab Business Week, November 19th, 2006

Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development.

The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics but also by geometry. Though created specifically for the study of breast tissue, this model should also be applicable to the study of tissue development in other organs as well.

"Our results reveal that tissue geometry can control the...

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