Ischemia Therapy
Studies from Astellas Pharma, Inc. have provided new data on ischemia therapy
Published in Lab Business Week, January 21st, 2007
Fresh data on ischemia are presented in the report "Tacrolimus (FK506) attenuates biphasic cytochrome c release and Bad phosphorylation following transient cerebral ischemia in mice. Tacrolimus (FK506) has a neuroprotective action on cerebral infarction produced by cerebral ischemia, however, detailed mechanisms underlying this action have not been fully elucidated. We examined temporal profiles of survival-and death-related signals, Bad phosphorylation, release of cytochrome c (cyt.c), activation of caspase 3 and DNA fragmentation in the brain during and after middle cerebral artery occlusion (MCAo) in mice, and then examined the effect of tacrolimus on these signals," scientists writing...
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Source: Lab Business Week (2007-01-21)
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