Breast Cancer Genetics
Studies from Chester Beatty Laboratories yield new data on breast cancer genetics
Published in Lab Business Week, April 29th, 2007
Investigators publish new data in the report "BRCA1 dysfunction in sporadic basal-like breast cancer. Basal-like breast cancers form a distinct subtype of breast cancer characterized by the expression of markers expressed in normal basal/myoepithelial cells. Breast cancers arising in carriers of germline BRCA1 mutations are predominately of basal-like type, suggesting that BRCA1 dysfunction may play a role in the pathogenesis of sporadic basal-like cancers," scientists in London, the United Kingdom report.
"We analysed 37 sporadic breast cancers expressing the basal marker cytokeratin 5/6, and age-and grade-matched controls, for downregulation of BRCA1. Although BRCA1...
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Source: Lab Business Week (2007-04-29)
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