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Studies from Ajinomoto Co., Inc. provide new data on life sciences

Published in Lab Business Week, April 29th, 2007

Data detailed in "mGluR1 in the fundic glands of rat stomach" have been presented. According to recent research from Kawasaki, Japan, "L-glutamate not only confers cognitive discrimination for umami taste in the oral cavity, but also conveys sensory information to vagal afferent fibers in the gastric mucosa. We used RT-PCR, western blotting, and immunohistochemistry to demonstrate that mGluR1 is located in glandular stomach."

"Double staining revealed that mGluR1 is found at the apical membrane of chief cells and possibly in parietal cells. Moreover, a diet with 1% l-glutamate induced changes in the expression of pepsinogen C mRNA in stomach mucosa," wrote Gabriel A.M....

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