Developmental Biology

Data from The Jackson Laboratory advance knowledge in developmental biology

Published in Lab Business Week, June 3rd, 2007

Investigators publish new data in the report "Oocytes are required for the preantral granulosa cell to cumulus cell transition in mice. Preantral granulosa cells (PAGCs) differentiate into cumulus cells following antrum formation. Cumulus cells, but not PAGCs, are competent to undergo expansion," scientists writing in the journal Developmental Biology report.

"Experiments reported here tested the respective roles of both oocytes and FSH in the transition of preantral granulosa cells to cumulus cells competent to undergo expansion. PAGC-oocyte complexes were cultured with or without a low dose of FSH (0.005 IU/ml) and isolated PAGCs were cultured with or without...

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Source: Lab Business Week (2007-06-03)

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