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Rheoscience and Dr. Reddy's Commence the First Phase III Trial of Balaglitazone (DRF 2593)

Published in Lab Business Week, August 19th, 2007

Rheoscience A/S and Dr. Reddy's Laboratories (NYSE:RDY) announced that the first patient has been dosed in a Phase III study with Balaglitazone (DRF2593-307), which is an insulin sensitizer that acts as a partial PPAR (peroxisome proliferator-activated receptor) gamma agonist. The study is the first in a series of planned Phase III trials which will investigate the safety and efficacy of Balaglitazone, as an oral anti-diabetic drug.

Balaglitazone is a second generation of PPAR gamma agonist with only partial agonistic properties, which in clinical phase II studies have shown to have glucose lowering capabilities and to be body-weight neutral. In preclinical experiments,...

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