Ischemia Prevention

Reports on ischemia prevention findings from Robert S. Dow Neurobiology Laboratories provide new insights

Published in Lab Business Week, March 9th, 2008

Researchers detail in 'Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism,' new data in ischemia. According to a study from the United States, "The rate of ischemic brain injury varies with the brain region, requiring only hours in striatum but days in hippocampus. Such maturation implies the existence of endogenous neuroprotective mechanisms."

"Adenosine is an endogenous neuroprotectant regulated by adenosine kinase (ADK). To investigate, whether adenosine might play a role in protecting the hippocampus after focal ischemia, we subjected transgenic mice, which overexpress ADK in hippocampal neurons...

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Source: Lab Business Week (2008-03-09)

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