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Gene Therapy

Researchers from Macrogen Inc. report details of new studies and findings in the area of gene therapy

Published in Lab Business Week, March 23rd, 2008

Data detailed in 'Genome-wide combination profiling of copy number and methylation offers an approach for deciphering misregulation and development in cancer cells' have been presented. According to a study from Seoul, Korea, "Copy number changes and DNA methylation alterations are crucial to gene regulation in mammals. Recently, a number of microarray studies have been based on copy number and DNA methylation alterations in order to find clinical biomarkers of carcinogenesis."

"In this study, we attempted to combine profiles of copy number and methylation patterns in four human cancer cell lines using BAC microarray-based approaches and we detected several clinically...

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