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Research from GlaxoSmithKline reveals new findings on life sciences

Published in Lab Business Week, April 20th, 2008

Data detailed in 'Pharmacological onomastics: what's in a name' have been presented. According to a study from the United States, "Drugs are named for their primary receptor target and overt action (agonism, antagonism) but the observation of multiple or collateral efficacies emanating from drugs activating a single receptor target is posing a challenge for drug classification and nomenclature. With increasing abilities to detect alteration in cellular function has come the identification of efficacies that are not necessarily manifest in obvious changes in cell response."

"Specifically, some agonists selectively activate cellular pathways, demonstrate phenotypic...

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