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Apoptosis Cell Biology
Research from Japan Science and Technology Corporation provides new data about apoptosis cell biology
May 18th, 2008
Investigators publish new data in the report 'Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.' According to a study from Tokyo, Japan, "Extracellular ATP, an autocrine or paracrine intercellular transmitter, is known to induce apoptosis in macrophages. However, the precise signaling mechanisms of ATP-induced apoptosis remain to be elucidated." "Here we showed that activation of p38 mitogen-activated protein kinase (MAPK) plays a critical role in ATP-induced apoptosis. p38 activation and apoptosis in macrophages were induced by ATP. ATP-induced apoptosis was mediated in part by...
Source: Lab Business Week (2008-05-18)
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