Enzyme Research

Report summarizes enzyme research study findings from Cold Spring Harbor Laboratory

Published in Lab Business Week, July 6th, 2008

Researchers detail in 'On helicases and other motor proteins,' new data in enzyme research. "Helicases are molecular machines that utilize energy derived from ATP hydrolysis to move along nucleic acids and to separate base-paired nucleotides. The movement of the helicase can also be described as a stationary helicase that pumps nucleic acid," scientists in the United States report.

"Recent structural data for the hexameric E1 helicase of papillomavirus in complex with single-stranded DNA and MgADP has provided a detailed atomic and mechanistic picture of its ATP-driven DNA translocation. The structural and mechanistic features of this helicase are compared with the...

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Source: Lab Business Week (2008-07-06)

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