Drug Development
Research in the area of drug development reported from F. Hoffmann-LaRoche Ltd.
Published in Lab Business Week, July 20th, 2008
"The extent is defined as the ratio of free brain concentration to free plasma concentration at steady state. For all central nervous system ( CNS) drug discovery programs, optimization of the extent of brain penetration should focus on designing and selecting compounds having low efflux transport at the blood- brain barrier ( BBB). The time to reach...
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Source: Lab Business Week (2008-07-20)
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