Atherosclerosis Vaccines
Scientists at Gorlaeus Laboratories report research in atherosclerosis vaccines
Published in Lab Business Week, April 4th, 2010
Fresh data on atherosclerosis are presented in the report 'Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice.' "Modification of lipoproteins plays an important role in the development of atherosclerosis. Oxidatively modified low-density lipoprotein (oxLDL) has a number of pro-inflammatory effects, whereas immunization with various forms of oxLDL is able to reduce atherosclerosis," scientists in Netherlands report.
"The uptake of modified LDL by dendritic cells (DCs) and the presentation of epitopes thereof may form an important step in the immunomodulatory effects of LDL. In this study, we...
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Source: Lab Business Week (2010-04-04)
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