Susan Hasty, Publisher
Table of Contents . . . May 7th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Lab Law Weekly | Other Publications
Aclara BioSciences - Four U.S. patents issued for eTag, nanofluidic technologies
Aletheon Pharmaceuticals, Inc. - NeoRx sells Pretarget intellectual property, announces resignation of VP
Americans for Nonsmokers' Rights - Study shows smoke free law slashed heart attack rate 40%
Avitar, Inc. - ORALscreen declared suitable for drug enforcement in Japan
Blue Cross & Blue Shield of Rhode Island - Rhode Island insurance giant under fire for rising rates, perks
ChromaVision Medical Systems - U.S. patent issued covers image analysis
End-Stage Renal Disease - Medicare initiative aims to increase use of fistulas in providing hemodialysis
Ethics - Gene therapy studies show first successes
Legal Issues - Judge dismisses Magee Pap smear lawsuit
Legal Issues - New York heart doctor sues hospital over suspension
Legal Issues - Two lawsuits filed in bacterial outbreak at Pittsburgh hospital
Legal Issues - Two new federal probes of Tenet hospitals launched
Mayo Foundation for Medical Education - Genaissance inks agreements for cardiac tests
Medicaid - Admissions to Florida hospitals surge as state Senate seeks cuts
Mental Health - Judges say patients' unnecessary institutionalization in Pennsylvania is an injustice
Tokyo Medical & Dental University - BMP-2 modulates proliferation and differentiation of gastric cancer cells
Aarhus University - Epitope from Epstein-Barr virus protein elicits sustained immune response
Affymetrix, Inc. - Expanded genomic technologies licensing program launched
Alcohol Research - New University of Alabama Birmingham center will toast to good health
American Chiropractic Association - Chiropractors urge Americans to walk 2000 steps per day
American College of Chest Physicians - Office spirometry testing improves early detection of COPD, study shows
Ardais Corporation - Aventis deal expanded to support target validation efforts
Aspect Medical Systems - Case made for using awareness monitoring in surgical patients
Atomic Energy Commission, Fontenay-aux-Roses - Astrocyte-induced matrix remodeling may mediate HIV-related neurodegeneration
Avant Immunotherapeutics, Inc. - Complement inhibition license deal signed with Adprotech
Bayer Consumer Care - Report: Aspirin's cardioprotective benefits far outweigh risks
Brown Medical School - Patients who receive kidneys from older donors do well
Brown University - Recombinant AAV-2 useful as anti-HIV RNAi vector
California Institute of Technology - Many novel cAMP response protein binding sites present in E. coli
Cancer Research U.K - Skin cancer time bomb for young Britons
Carnegie Mellon University - Spouse social control associated with poor health behavior in prostate cancer
Chelsea and Westminster Hospital - Dose escalation unnecessary in patients switching to nevirapine from efavirenz
Chiba University - Adult cardiac Sca-1+ cells have stem-cell potential
Chinese University of Hong Kong - Musk substitution doesn't alter the hepatoprotective actions of Pien Tze Huang
Chonbuk National University - Modification of cholera toxin B subunit enhances expression in plants
Chosun University, Dwangju - System L amino acid transporter rationale for oral cancer therapy
Churchill Hospital - Neither hepatitis B nor C viruses associate with vulval lichen planus
Ciphergen Biosystems, Inc. - Biomarker Patterns Software 5.0 released for discovering protein patterns
Commonwealth Scientific & Industrial Res. Org. - High-calcium diet minimizes bone turnover during weight loss
Connetics Corporation - NDA for Extina has been accepted for filing by the FDA
Contraception - Research making progress in quest for male version of birth control pill
Cook Incorporated - Trial of Zenith TX2 Thoracic graft started
Cosmix Molecular Biologicals GmbH - Biotech firm acquires rights to mRNA-peptide display
Cutting Edge Information - 88% of pharmaceutical companies use thought leaders for needs assessments
Cutting Edge Information - Clinical trials extend 3-5 months due to patient recruitment, research shows
Cutting Edge Information - Companies "evergreen" pharmaceuticals for longer market share
Cylene Pharmaceuticals, Inc. - Oncology company announces new VP of clinical operations
Decision Resources, Inc. - Drug-treated diabetic retinopathy population to quadruple by 2012
Digene Corp. - Study documents cost-effectiveness of HPV test in cervical cancer prevention
Duke University - Dendritic cell vaccine generates specific antipancreatic cancer T cells
Duke University - Prescription of opioids for back pain needs improvement
East Carolina University - Decision support system developed for measurement of operational efficiency
Entelos, Inc. - Milestone payment received for delivery of novel targets to Organon
Enzo Biochem, Inc. - Preclinical study points to development of glucosylceramide
European Molecular Biology Lab - Researchers discover a surprising link between inflammation and anemia
Favrille, Inc. - Immunotherapy company files for IPO, raises $44M in private placement
Fitness & Wellness - Only 35% of students pass Connecticut physical fitness test
Forbes Medi-Tech, Inc. - European phase II trial results for FM-VP4 announced; endpoints met
Genaera Corp. - Company receives patent for key mucoregulator therapeutic target
Genentech Inc. - Novel tissue-restricted angiogenic factors regulate steroidogenic function
GlaxoSmithKline Pharmaceuticals - Proton magnetic resonance spectroscopy can monitor glioma response to treatment
HIV/AIDS Treatment - Arkansas plans waiting list for HIV drugs
HomMed, LLC - Telemonitoring company posts record shipments in first quarter of 2004
Huddinge University Hospital - Fibrinolytic factors abound in the tissues of endometriosis patients
INSERM U412, Lyon - Lentiviral vectors can be re-engineered to optimize gene delivery
IR Biosciences Holdings, Inc. - ImmuneRegen BioSciences parent company announces 2-for-1 forward stock split
Imperial College London - Newborn lambs' central heating system could aid fat busting in humans
Influenza Drug - Flu shot makers say orders for next season filling up fast
Institute of Cancer Research, Surrey - Thyroglobulin polymorphic variation increases non-medullary thyroid cancer risk
Joslin Diabetes Center - Optimal fasting and postprandial glucose important in diabetes
Kyowa Hakko Kogyo Co. Ltd - K579 is long-acting hypoglycemic agent
Kyung Hee University, Seoul - Cerebral infarction susceptibility with TNF-alpha gene polymorphism
Lab. for Integrative Neurosci & Endocrin., Bristol - Endomorphins expressed by some immune cells
Lark Technologies, Inc. - Genomic-services company reports record revenue and net income for 2003
Leiden University - Schistosome carbohydrates are dominant epitopes in humoral immune response
Leiden University Medical Center - Acipimox enhances spontaneous growth hormone secretion in obese women
Ligand Pharmaceuticals, Inc. - Studies support Targretin's activity in NSCLC
Lipid Sciences, Inc. - Role of HDL therapy for cardiovascular disease highlighted in journal
Lupin, Ltd. - Suprax launched in the U.S.
M.D. Anderson Cancer Center - HIV synthetic peptide-cocktail prevents SHIV transmission
M.D. Anderson Cancer Center - Longevity gene may also predict better outcome for breast cancer patients
Massachusetts General Hospital - Stromal composition helps diagnosis of biphasic lesions of the breast
McGill University, Montreal - The Shc adaptor protein is significant to the induction of tumor angiogenesis
Medical College of Georgia - Study pursues markers to improve ovarian cancer treatment, diagnosis
Medical Services International, Inc. - VScan HIV Rapid Test Kits placed in dispensaries in Southeast Asia
Medicos Laboratories, Inc. - Inamco re-announces the completions of multimillion-dollar acquisitions
Medtronic, Inc. - "Off-pump" coronary bypass surgery has similar outcomes, lower cost
Medtronic, Inc. - Japan approves Sprinter balloon catheter
Medwave, Inc. - Insiders purchase blood-pressure-measurement company securities
Memorial University of Newfoundland - HAART-induced recovery of HIV-specific immunity described
MicroIslet, Inc. - Diabetes-focused company reports first quarter net loss of $1.2M
Mt. Sinai School of Medicine - Cyclin-dependent kinase inhibitor p21 induces Flt3-ITD leukemogenesis
Munster University Hospital - Digital oncology documentation system integration increases quality assurance
NPS Pharmaceuticals, Inc. - Pivotal study begins with teduglutide in patients with SBS
Netherlands Cancer Institute - Gene plays major role in formation of stem cells and cancer
Neurochem, Inc. - Neurological company consolidates operations as it reaches new level of growth
Northwestern Memorial Hospital - Computerized prescriber order entry systems may not decrease patient harm
Northwestern University - Alarming rise in incidence of lung cancer and death seen in women
Novavax, Inc. - Rahul Singhvi named VP, pharmaceutical development and manufacturing operations
Oncolytics Biotech Inc. - Biotechnology company appoints new member to board of directors
Organon USA Inc. - Pharmaceutical company to close manufacturing facility
Par Pharmaceutical, Inc. - FDA issues final approval for ribavirin capsules
Philadelphia College of Osteopathic Medicine - Researchers link common airborne bacterium to Alzheimer disease
Prana Biotechnology, Ltd. - Paper further validates brain protein theory
Pro-Pharmaceuticals, Inc. - Drug development company raises $4.5 million
Purdue University - Self-assembling "nanotubes" offer promise for future artificial joints
Quidel Corporation - Diagnostics company expects first quarter total revenues of $19.7M
Refractec, Inc. - FDA approves vision technology for presbyopic baby boomers
Seoul National University - Genetic polymorphisms in PPAR-delta associated with obesity
Shanghai Institutes for Biological Sciences - Metastasis-associated protein analysis indicates different metastasis roles
Slovak Academy of Sciences - DNA vaccines encoding ras epitopes and B7.1 reduced tumor burden in rats
SoLar Pharmaceuticals, Inc. - Pharmaceutical company announces appointment of executive vice president
Spectrum Pharmaceuticals, Inc. - Phase II elsamitrucin trial launched for refractory non-Hodgkin lymphoma
Stryker Corporation - Medical device company announces appointment of new president
Sucampo Pharmaceuticals, Inc. - Pharmaceutical company appoints three new members to board of directors
Target Discovery Inc. - Collaboration to test theories concerning the mechanism of childhood autism
Tehran University of Med. Science & Health Service - Serum levels of zinc affect bone mineral density in beta-thalassemic youth
Tel Aviv Sourasky Medical Center - Intracytoplasmic sperm injection works when oocytes have abnormal structures
Telemedicine - Video technology aids home healthcare
Thomas Jefferson University - Polypeptides in hepatitis B virus carriers correlate with disease status
Tohoku University - Transcription factor Ets-1 is essential to the induction of angiopoietin-2
Tokyo Medical & Dental University - Prostaglandin E2 regulates metalloproteinase-3 in gingival fibroblasts
Trinity College Dublin - Antigen-specific regulatory T-cell function reviewed
Tyco Healthcare Group LP - Patent infringement lawsuit filed for reusable sharps containers
U.S. Army - Mental health symptoms common at Pentagon after 9/11
U.S. Centers for Disease Control & Prevention - Rickettsia parkeri is cause of spotted fever rickettsiosis in U.S.
U.S. Centers for Disease Control & Prevention - Characteristics of children who leave WIC program identified
U.S. Centers for Disease Control & Prevention - Genes from 1918 pandemic influenza virus used to test pathogenicity
U.S. Centers for Disease Control & Prevention - Prairie dogs transmit monkeypox to humans
U.S. Centers for Disease Control & Prevention - RNA recombination plays induces genomic change in coxsackie B viruses
U.S. Centers for Disease Control and Prevention - Binge drinking declined in late '80s, rose again in late '90s
U.S. Centers for Disease Control and Prevention - CDC: Flu season fairly typical, despite severe start in the West
U.S. Food & Drug Administration - UV exposure decreases skin thickness
U.S. Food and Drug Administration - Government health authority warns against eight supplements
U.S. National Inst. of Standards and Technology - Glowing microspheres improve fluorescence measurements
U.S. National Institutes of Health - Anti-LFA-1 delays viral clearance in RSV infection
U.S. National Institutes of Health - Reengineered salivary glands act as bioreactors for systemic gene therapies
UFR Pharmacie, Reims Cedex - P-glycoprotein-derived peptides inhibited multidrug resistance of tumors
Univ. of California, Los Angeles - Liver X receptors regulate macrophage-produced proangiogenic growth factor
Univ. of California, Los Angeles - Sentinel lymph node tumor status is important for staging melanoma
Univ. of Medicine and Dentistry of New Jersey - Eye disorder is high among people with type 1 diabetes mellitus
Univ. of Texas Medical Branch, Galveston - Frozen section and permanent analysis of sentinel nodes are equivalent
Univ. of Texas, Dallas - Antisense RNA molecules select for molecules linked to sickle cell disease
Univ. of Wales, College of Cardiff - Study shows there's a learning curve in performing sentinel node biopsy
Universitat Autonoma de Barcelona - Pasteurella multocida contains multiple hemoglobin-binding proteins
University College London - New gene linked to brain disorder
University Medical Center, Utrecht - Specific chromosomes may be linked to the age at which menopause commences
University of Alabama - Nasal Flt3 ligand cDNA elicits dendritic cells for enhanced mucosal immunity
University of Barcelona - Novel CD4+ T-helper lymphocyte epitope identified in hepatitis A virus
University of California, San Francisco - Lytic KSHV infection inhibits host gene expression
University of Cambridge - Fc gamma RIIb balances pathogen clearance and consequences of sepsis
University of Cambridge - Heat shock protein promotes presentation of antigens to immune system
University of Chicago - E. coli LPS induces heat shock protein 25 in intestinal cells
University of Chicago - Socioeconomic inequality of obesity exists in the United States
University of Cincinnati Medical Center - Novel molecular assays detect mycobacteria, pseudomonads in metalworking fluids
University of Cologne - Adenoviral vectors for gene transfer and therapy reviewed
University of Edinburgh - CPI-17 associated with protein kinase C and casein kinase I
University of Geneva Hospital - Handrub promotion extremely cost-effective
University of Giessen - Bulimia nervosa patients show no differences at disgust control centers
University of Hong Kong - Response to plasmid DNAs encoding SARS-CoV spike gene fragments characterized
University of Lausanne - Amoebae-resisting bacteria isolated from amoebal coculture
University of Lausanne - Uniaxial accelerometry useful for assessing energy expenditure
University of Laval - Whey proteins and enzymatic digests have immunomodulatory activity
University of Medicine and Dentistry of New Jersey - Mast cells have protective role during urinary bladder infections
University of Michigan - Age-related macular degeneration may have gene-linked origins
University of Michigan - Lung doctors most likely to have flu vaccine on hand
University of Michigan - The stillborn birth rate is high among Zimbabwean women
University of Munich - CpG-A and CpG-B oligonucleotides stimulate CD8+ T-cell responses in vitro
University of Nantes - Origin and maturation of CD11b+Gr-1+ iMacs elucidated
University of North Carolina - Nonculturable bacteria thrive in the human urinary tract
University of North Dakota - Hyperacetylation define classes of acetylated SV40 chromosomes
University of Pennsylvania - bis-(Papaverine) analogue potent muscle relaxant in vitro
University of Portsmouth - Macrophages expressing P2X4 play key role in Duchenne pathogenesis
University of Queensland - Effect of Candida infection on murine hematopoiesis characterized
University of Tokyo - Breast cancer patients self-participation depends on length of consultation
University of Toronto - Mortality rate higher for homeless women in Toronto
University of Toronto - Perinatal neural stem cells have bidirectional stress-dependent plasticity
University of Tsukuba - SREBP-1c expression in liver of diabetic mice is insulin independent
VIRxSYS Corporation - Board recommends dosing of final two patients in VRX496 trial
Vical Incorporated - Biopharmaceutical developer announces patents for gene delivery technologies
Victor Segalen University - E152 amino acid region of HIV integrase characterized
Virginia Polytech Institute - Steroid-linked taxol analogues cytotoxic to cancer cells in vitro
WHO Collaborating Centre, Semarang - Early aggressive combination treatment can halt radiographic progression
Washington University - Calorie restriction drastically reduces risk of heart attack, stroke, diabetes
Washington University - Control of diabetes after transplantation of pig pancreatic anlagen
Wonkwang University - Pv30 antigen valuable for malaria serodiagnosis in Korea
World Health Organization - World to be polio-free by next year, but losing AIDS war
Yamagata University - LPS-induced COX-2 expression attenuated in diabetic blood vessels
Zargis Medical Corp. - Update announced on Zargis Acoustic Cardioscan System FDA submission
Zevex International, Inc. - Medical device manufacturer reports revenue increase in 2003
Zonagen, Inc. - Progenta breast cancer treatment data presented at cancer research meeting
ZymoGenetics - U.S. FDA issues agreement for Interleukin 21 phase I cancer study
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