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Lab Law Weekly

Susan Hasty, Publisher

Table of Contents . . . May 7th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Law Weekly | Other Publications

Aclara BioSciences - Four U.S. patents issued for eTag, nanofluidic technologies

Aletheon Pharmaceuticals, Inc. - NeoRx sells Pretarget intellectual property, announces resignation of VP

Americans for Nonsmokers' Rights - Study shows smoke free law slashed heart attack rate 40%

Avitar, Inc. - ORALscreen declared suitable for drug enforcement in Japan

Blue Cross & Blue Shield of Rhode Island - Rhode Island insurance giant under fire for rising rates, perks

ChromaVision Medical Systems - U.S. patent issued covers image analysis

End-Stage Renal Disease - Medicare initiative aims to increase use of fistulas in providing hemodialysis

Ethics - Gene therapy studies show first successes

Legal Issues - Judge dismisses Magee Pap smear lawsuit

Legal Issues - New York heart doctor sues hospital over suspension

Legal Issues - Two lawsuits filed in bacterial outbreak at Pittsburgh hospital

Legal Issues - Two new federal probes of Tenet hospitals launched

Mayo Foundation for Medical Education - Genaissance inks agreements for cardiac tests

Medicaid - Admissions to Florida hospitals surge as state Senate seeks cuts

Mental Health - Judges say patients' unnecessary institutionalization in Pennsylvania is an injustice

Tokyo Medical & Dental University - BMP-2 modulates proliferation and differentiation of gastric cancer cells

Aarhus University - Epitope from Epstein-Barr virus protein elicits sustained immune response

Affymetrix, Inc. - Expanded genomic technologies licensing program launched

Alcohol Research - New University of Alabama Birmingham center will toast to good health

American Chiropractic Association - Chiropractors urge Americans to walk 2000 steps per day

American College of Chest Physicians - Office spirometry testing improves early detection of COPD, study shows

Ardais Corporation - Aventis deal expanded to support target validation efforts

Aspect Medical Systems - Case made for using awareness monitoring in surgical patients

Atomic Energy Commission, Fontenay-aux-Roses - Astrocyte-induced matrix remodeling may mediate HIV-related neurodegeneration

Avant Immunotherapeutics, Inc. - Complement inhibition license deal signed with Adprotech

Bayer Consumer Care - Report: Aspirin's cardioprotective benefits far outweigh risks

Brown Medical School - Patients who receive kidneys from older donors do well

Brown University - Recombinant AAV-2 useful as anti-HIV RNAi vector

California Institute of Technology - Many novel cAMP response protein binding sites present in E. coli

Cancer Research U.K - Skin cancer time bomb for young Britons

Carnegie Mellon University - Spouse social control associated with poor health behavior in prostate cancer

Chelsea and Westminster Hospital - Dose escalation unnecessary in patients switching to nevirapine from efavirenz

Chiba University - Adult cardiac Sca-1+ cells have stem-cell potential

Chinese University of Hong Kong - Musk substitution doesn't alter the hepatoprotective actions of Pien Tze Huang

Chonbuk National University - Modification of cholera toxin B subunit enhances expression in plants

Chosun University, Dwangju - System L amino acid transporter rationale for oral cancer therapy

Churchill Hospital - Neither hepatitis B nor C viruses associate with vulval lichen planus

Ciphergen Biosystems, Inc. - Biomarker Patterns Software 5.0 released for discovering protein patterns

Commonwealth Scientific & Industrial Res. Org. - High-calcium diet minimizes bone turnover during weight loss

Connetics Corporation - NDA for Extina has been accepted for filing by the FDA

Contraception - Research making progress in quest for male version of birth control pill

Cook Incorporated - Trial of Zenith TX2 Thoracic graft started

Cosmix Molecular Biologicals GmbH - Biotech firm acquires rights to mRNA-peptide display

Cutting Edge Information - 88% of pharmaceutical companies use thought leaders for needs assessments

Cutting Edge Information - Clinical trials extend 3-5 months due to patient recruitment, research shows

Cutting Edge Information - Companies "evergreen" pharmaceuticals for longer market share

Cylene Pharmaceuticals, Inc. - Oncology company announces new VP of clinical operations

Decision Resources, Inc. - Drug-treated diabetic retinopathy population to quadruple by 2012

Digene Corp. - Study documents cost-effectiveness of HPV test in cervical cancer prevention

Duke University - Dendritic cell vaccine generates specific antipancreatic cancer T cells

Duke University - Prescription of opioids for back pain needs improvement

East Carolina University - Decision support system developed for measurement of operational efficiency

Entelos, Inc. - Milestone payment received for delivery of novel targets to Organon

Enzo Biochem, Inc. - Preclinical study points to development of glucosylceramide

European Molecular Biology Lab - Researchers discover a surprising link between inflammation and anemia

Favrille, Inc. - Immunotherapy company files for IPO, raises $44M in private placement

Fitness & Wellness - Only 35% of students pass Connecticut physical fitness test

Forbes Medi-Tech, Inc. - European phase II trial results for FM-VP4 announced; endpoints met

Genaera Corp. - Company receives patent for key mucoregulator therapeutic target

Genentech Inc. - Novel tissue-restricted angiogenic factors regulate steroidogenic function

GlaxoSmithKline Pharmaceuticals - Proton magnetic resonance spectroscopy can monitor glioma response to treatment

HIV/AIDS Treatment - Arkansas plans waiting list for HIV drugs

HomMed, LLC - Telemonitoring company posts record shipments in first quarter of 2004

Huddinge University Hospital - Fibrinolytic factors abound in the tissues of endometriosis patients

INSERM U412, Lyon - Lentiviral vectors can be re-engineered to optimize gene delivery

IR Biosciences Holdings, Inc. - ImmuneRegen BioSciences parent company announces 2-for-1 forward stock split

Imperial College London - Newborn lambs' central heating system could aid fat busting in humans

Influenza Drug - Flu shot makers say orders for next season filling up fast

Institute of Cancer Research, Surrey - Thyroglobulin polymorphic variation increases non-medullary thyroid cancer risk

Joslin Diabetes Center - Optimal fasting and postprandial glucose important in diabetes

Kyowa Hakko Kogyo Co. Ltd - K579 is long-acting hypoglycemic agent

Kyung Hee University, Seoul - Cerebral infarction susceptibility with TNF-alpha gene polymorphism

Lab. for Integrative Neurosci & Endocrin., Bristol - Endomorphins expressed by some immune cells

Lark Technologies, Inc. - Genomic-services company reports record revenue and net income for 2003

Leiden University - Schistosome carbohydrates are dominant epitopes in humoral immune response

Leiden University Medical Center - Acipimox enhances spontaneous growth hormone secretion in obese women

Ligand Pharmaceuticals, Inc. - Studies support Targretin's activity in NSCLC

Lipid Sciences, Inc. - Role of HDL therapy for cardiovascular disease highlighted in journal

Lupin, Ltd. - Suprax launched in the U.S.

M.D. Anderson Cancer Center - HIV synthetic peptide-cocktail prevents SHIV transmission

M.D. Anderson Cancer Center - Longevity gene may also predict better outcome for breast cancer patients

Massachusetts General Hospital - Stromal composition helps diagnosis of biphasic lesions of the breast

McGill University, Montreal - The Shc adaptor protein is significant to the induction of tumor angiogenesis

Medical College of Georgia - Study pursues markers to improve ovarian cancer treatment, diagnosis

Medical Services International, Inc. - VScan HIV Rapid Test Kits placed in dispensaries in Southeast Asia

Medicos Laboratories, Inc. - Inamco re-announces the completions of multimillion-dollar acquisitions

Medtronic, Inc. - "Off-pump" coronary bypass surgery has similar outcomes, lower cost

Medtronic, Inc. - Japan approves Sprinter balloon catheter

Medwave, Inc. - Insiders purchase blood-pressure-measurement company securities

Memorial University of Newfoundland - HAART-induced recovery of HIV-specific immunity described

MicroIslet, Inc. - Diabetes-focused company reports first quarter net loss of $1.2M

Mt. Sinai School of Medicine - Cyclin-dependent kinase inhibitor p21 induces Flt3-ITD leukemogenesis

Munster University Hospital - Digital oncology documentation system integration increases quality assurance

NPS Pharmaceuticals, Inc. - Pivotal study begins with teduglutide in patients with SBS

Netherlands Cancer Institute - Gene plays major role in formation of stem cells and cancer

Neurochem, Inc. - Neurological company consolidates operations as it reaches new level of growth

Northwestern Memorial Hospital - Computerized prescriber order entry systems may not decrease patient harm

Northwestern University - Alarming rise in incidence of lung cancer and death seen in women

Novavax, Inc. - Rahul Singhvi named VP, pharmaceutical development and manufacturing operations

Oncolytics Biotech Inc. - Biotechnology company appoints new member to board of directors

Organon USA Inc. - Pharmaceutical company to close manufacturing facility

Par Pharmaceutical, Inc. - FDA issues final approval for ribavirin capsules

Philadelphia College of Osteopathic Medicine - Researchers link common airborne bacterium to Alzheimer disease

Prana Biotechnology, Ltd. - Paper further validates brain protein theory

Pro-Pharmaceuticals, Inc. - Drug development company raises $4.5 million

Purdue University - Self-assembling "nanotubes" offer promise for future artificial joints

Quidel Corporation - Diagnostics company expects first quarter total revenues of $19.7M

Refractec, Inc. - FDA approves vision technology for presbyopic baby boomers

Seoul National University - Genetic polymorphisms in PPAR-delta associated with obesity

Shanghai Institutes for Biological Sciences - Metastasis-associated protein analysis indicates different metastasis roles

Slovak Academy of Sciences - DNA vaccines encoding ras epitopes and B7.1 reduced tumor burden in rats

SoLar Pharmaceuticals, Inc. - Pharmaceutical company announces appointment of executive vice president

Spectrum Pharmaceuticals, Inc. - Phase II elsamitrucin trial launched for refractory non-Hodgkin lymphoma

Stryker Corporation - Medical device company announces appointment of new president

Sucampo Pharmaceuticals, Inc. - Pharmaceutical company appoints three new members to board of directors

Target Discovery Inc. - Collaboration to test theories concerning the mechanism of childhood autism

Tehran University of Med. Science & Health Service - Serum levels of zinc affect bone mineral density in beta-thalassemic youth

Tel Aviv Sourasky Medical Center - Intracytoplasmic sperm injection works when oocytes have abnormal structures

Telemedicine - Video technology aids home healthcare

Thomas Jefferson University - Polypeptides in hepatitis B virus carriers correlate with disease status

Tohoku University - Transcription factor Ets-1 is essential to the induction of angiopoietin-2

Tokyo Medical & Dental University - Prostaglandin E2 regulates metalloproteinase-3 in gingival fibroblasts

Trinity College Dublin - Antigen-specific regulatory T-cell function reviewed

Tyco Healthcare Group LP - Patent infringement lawsuit filed for reusable sharps containers

U.S. Army - Mental health symptoms common at Pentagon after 9/11

U.S. Centers for Disease Control & Prevention -  Rickettsia parkeri is cause of spotted fever rickettsiosis in U.S.

U.S. Centers for Disease Control & Prevention - Characteristics of children who leave WIC program identified

U.S. Centers for Disease Control & Prevention - Genes from 1918 pandemic influenza virus used to test pathogenicity

U.S. Centers for Disease Control & Prevention - Prairie dogs transmit monkeypox to humans

U.S. Centers for Disease Control & Prevention - RNA recombination plays induces genomic change in coxsackie B viruses

U.S. Centers for Disease Control and Prevention - Binge drinking declined in late '80s, rose again in late '90s

U.S. Centers for Disease Control and Prevention - CDC: Flu season fairly typical, despite severe start in the West

U.S. Food & Drug Administration - UV exposure decreases skin thickness

U.S. Food and Drug Administration - Government health authority warns against eight supplements

U.S. National Inst. of Standards and Technology - Glowing microspheres improve fluorescence measurements

U.S. National Institutes of Health - Anti-LFA-1 delays viral clearance in RSV infection

U.S. National Institutes of Health - Reengineered salivary glands act as bioreactors for systemic gene therapies

UFR Pharmacie, Reims Cedex - P-glycoprotein-derived peptides inhibited multidrug resistance of tumors

Univ. of California, Los Angeles - Liver X receptors regulate macrophage-produced proangiogenic growth factor

Univ. of California, Los Angeles - Sentinel lymph node tumor status is important for staging melanoma

Univ. of Medicine and Dentistry of New Jersey - Eye disorder is high among people with type 1 diabetes mellitus

Univ. of Texas Medical Branch, Galveston - Frozen section and permanent analysis of sentinel nodes are equivalent

Univ. of Texas, Dallas - Antisense RNA molecules select for molecules linked to sickle cell disease

Univ. of Wales, College of Cardiff - Study shows there's a learning curve in performing sentinel node biopsy

Universitat Autonoma de Barcelona -  Pasteurella multocida contains multiple hemoglobin-binding proteins

University College London - New gene linked to brain disorder

University Medical Center, Utrecht - Specific chromosomes may be linked to the age at which menopause commences

University of Alabama - Nasal Flt3 ligand cDNA elicits dendritic cells for enhanced mucosal immunity

University of Barcelona - Novel CD4+ T-helper lymphocyte epitope identified in hepatitis A virus

University of California, San Francisco - Lytic KSHV infection inhibits host gene expression

University of Cambridge - Fc gamma RIIb balances pathogen clearance and consequences of sepsis

University of Cambridge - Heat shock protein promotes presentation of antigens to immune system

University of Chicago -  E. coli LPS induces heat shock protein 25 in intestinal cells

University of Chicago - Socioeconomic inequality of obesity exists in the United States

University of Cincinnati Medical Center - Novel molecular assays detect mycobacteria, pseudomonads in metalworking fluids

University of Cologne - Adenoviral vectors for gene transfer and therapy reviewed

University of Edinburgh - CPI-17 associated with protein kinase C and casein kinase I

University of Geneva Hospital - Handrub promotion extremely cost-effective

University of Giessen - Bulimia nervosa patients show no differences at disgust control centers

University of Hong Kong - Response to plasmid DNAs encoding SARS-CoV spike gene fragments characterized

University of Lausanne - Amoebae-resisting bacteria isolated from amoebal coculture

University of Lausanne - Uniaxial accelerometry useful for assessing energy expenditure

University of Laval - Whey proteins and enzymatic digests have immunomodulatory activity

University of Medicine and Dentistry of New Jersey - Mast cells have protective role during urinary bladder infections

University of Michigan - Age-related macular degeneration may have gene-linked origins

University of Michigan - Lung doctors most likely to have flu vaccine on hand

University of Michigan - The stillborn birth rate is high among Zimbabwean women

University of Munich - CpG-A and CpG-B oligonucleotides stimulate CD8+ T-cell responses in vitro

University of Nantes - Origin and maturation of CD11b+Gr-1+ iMacs elucidated

University of North Carolina - Nonculturable bacteria thrive in the human urinary tract

University of North Dakota - Hyperacetylation define classes of acetylated SV40 chromosomes

University of Pennsylvania - bis-(Papaverine) analogue potent muscle relaxant in vitro

University of Portsmouth - Macrophages expressing P2X4 play key role in Duchenne pathogenesis

University of Queensland - Effect of Candida infection on murine hematopoiesis characterized

University of Tokyo - Breast cancer patients self-participation depends on length of consultation

University of Toronto - Mortality rate higher for homeless women in Toronto

University of Toronto - Perinatal neural stem cells have bidirectional stress-dependent plasticity

University of Tsukuba - SREBP-1c expression in liver of diabetic mice is insulin independent

VIRxSYS Corporation - Board recommends dosing of final two patients in VRX496 trial

Vical Incorporated - Biopharmaceutical developer announces patents for gene delivery technologies

Victor Segalen University - E152 amino acid region of HIV integrase characterized

Virginia Polytech Institute - Steroid-linked taxol analogues cytotoxic to cancer cells in vitro

WHO Collaborating Centre, Semarang - Early aggressive combination treatment can halt radiographic progression

Washington University - Calorie restriction drastically reduces risk of heart attack, stroke, diabetes

Washington University - Control of diabetes after transplantation of pig pancreatic anlagen

Wonkwang University - Pv30 antigen valuable for malaria serodiagnosis in Korea

World Health Organization - World to be polio-free by next year, but losing AIDS war

Yamagata University - LPS-induced COX-2 expression attenuated in diabetic blood vessels

Zargis Medical Corp. - Update announced on Zargis Acoustic Cardioscan System FDA submission

Zevex International, Inc. - Medical device manufacturer reports revenue increase in 2003

Zonagen, Inc. - Progenta breast cancer treatment data presented at cancer research meeting

ZymoGenetics - U.S. FDA issues agreement for Interleukin 21 phase I cancer study

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