University Hospital of Canarias

Cytoplasmic and perinuclear antineutrophil antibodies reported in patient

Published in Lab Law Weekly, June 4th, 2004

The presence of both cytoplasmic and perinuclear antineutrophil antibodies has been reported in a Henoch-Schonlein purpura patient.

Rheumatologists in Spain described "the case of a 60-year-old man who presented clinical and histopathological evidence of Henoch-Schonlein purpura.

"Antineutrophil antibodies (ANCA) showed positive results on an enzyme-linked immunosorbent assay and immunofluorescence for anti-myeloperoxidase and anti-proteinase 3 antibodies," according to I. Ferraz-Amaro and coauthors working at the University Hospital of Canarias.

"Dual positivity for both cytoplasmatic (C-ANCA) and perinuclear (P-ANCA)...

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Source: Lab Law Weekly (2004-06-04)

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