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Lab Law Weekly

Susan Hasty, Publisher

Table of Contents . . . September 10th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Law Weekly | Other Publications

AXM Pharma, Inc. - Oral drug delivery technology supply agreement executed for chewable products

Bradley Pharmaceuticals, Inc. - Acquisition of Bioglan Pharmaceuticals closes

Centers for Medicare & Medicaid Services - Medicare expands drugs available to help beneficiaries with severe illnesses

Humana Inc. - Kansas-Missouri healthcare system to join insurance company's Medicare PPO plan

Humane Society of the United States - Demographics of primate research in the United States analyzed

Legal Issues - Pharmaceutical supplier drops legal fight to help Americans buy drugs from Canada

Legal Issues - Vermont sues FDA over drug importation

North Mississippi Health Services - Company reaches agreement on discounts for uninsured patients

Pharmaceuticals - Pharmaceutical company gives up Chinese patent on popular diabetes drug

Prana Biotechnology Limited - Biotechnology added to drug watch list, settles patent litigation, names CEO

Prometheus Laboratories Inc. - Specialty pharmaceutical company gains settlement regarding patents

Tenet Healthcare Corporation - Hospital group yields documents requested by U.S. attorney's office

Thermage - Medical device company files preliminary injunction to stop Syneron shipment

AEterna Zentaris, Inc. - Agreement signed for fourth generation LHRH antagonist D-63153

Abiomed, Inc. - Device maker reports 47% increase in product revenues

Albert Szent Gyorgyi University - Interaction between NO and NAChR plays role in sleep/wake cycle

Altana AG - Pharmaceutical firm reports 13% growth rate in first half of 2004

Ambion - New RNA interference library launched

American Academy of Dermatology - Dermatologist offer various solutions for hereditary hair loss

American Oriental Bioengineering - Chinese biotech firm to be included in NAI China Small Cap Index

Aradigm Corporation - Drug delivery developer reports loss of $0.12 per share

Archemix Corp. - Phase I trial initiated for thrombin inhibitor, ARC183

Aristotle University of Thessaloniki - Historical background of obesity outlined

Aston University - Patient reactions to diabetes diagnosis can guide management strategies

Astro-Med, Inc. - Ambulatory sleep screener launched

Avigen, Inc. - FDA clears gene therapy trial for Parkinson disease

Avitar, Inc. - Diagnostics firm announces $1,250,000 private placement

BD Bioscience, San Jose - Cytokine flow cytometry analyzes T-cell responses to cytomegalovirus

Bates College - Genetics may determine gum disease in humans

Baylor College of Medicine - Live viral vaccines safe in patients with partial DiGeorge syndrome

Berna Biotech Ltd. - Biosafety aspects of live oral Vibrio cholerae vaccine strain examined

BioMarin Pharmaceutical, Inc. - Pharmaceutical firm reports loss of $0.86 per share, gives pipeline update

Bioenvision, Ltd. - First patients enter pivotal phase II study of clofarabine

Bioterrorism - Monmouth University developing system to detect disease, terror attacks

Blue Cross Blue Shield of Missouri - Blue Cross Blue Shield of Missouri implements doctor notification program

Boston University - Mitochondrial genome mutations may be found in hypertensive individuals

Boston University - Sun protection declines between the first and second summers of children's lives

Business & Finance - Insurance company announces $250 million purchase agreement

Cancer Patient Groups - U.K. patient organizations recommends Glivec for inoperapeable tumors

Cardiac Science, Inc. - Defibrillator maker reports 20% increase in revenue

CardioGenesis Corporation - Company gets guidance from FDA on percutaneous procedure

CardioMag - Heart-health scanner gets marketing, product quality certification

Centers for Medicare & Medicaid Services - HHS approves plan to continue allowing elderly to receive self-directed care

Central South University, Changsha - RhoC expression linked to poor prognosis

Chronimed, Inc. - Fuzeon maker reports strong Q4 and year-end results

ClearStep - ClearStep "invisible" braces launched in the U.K.

Cleveland Clinic - Stem cells have a role in myocardial regeneration

CollaGenex Pharmaceuticals, Inc. - Maker of dental and dermatology products names VPs

Columbia University - Glucose monitoring in intensive care patients results in reduction in mortality

Curie Institute, Paris - Novel method enables efficient reconstitution of membrane proteins into GUVs

Cutting Edge Information - Research shows pharmaceutical companies stay lean through outsourcing

DOBI Medical International, Inc. - Imaging company reports Q2 net loss of $1.6 million

DiagnoCure Inc. - Prostate cancer molecular test may address limitations of traditional testing

Diagnostic Hybrids, Inc. - Cell-culture provider receives investment from Summit Partners

Digene Corp. - In Q4, total revenue increased 36% to $25.9 million for HPV testmaker

EMC Microcollections GmbH - Relations between lipopeptide adjuvants and Toll-like receptor explored

Emory University - Positive self-concept linked to refusal of unprotected sex

Endocare, Inc. - Ablation company reports Q2 revenues of $8.3 million

Erasmus Medical Center - Utility of multi-detector row CT angiography reviewed

Erasmus Medical Center, Rotterdam - Screening high-risk women for cancer does not negatively impact short-term QOL

FIOCRUZ -  N. meningitidis vesicles and lipo-oligosaccharide protect against septic shock

Forschungszentrum Julich - A novel recovery approach for separation and concentration is described

Forschungszentrum Karlsruhe - Capacitive coupling technique improves biosensor response characteristics

Frost and Sullivan - Efficiency, productivity gains drive uptake of wireless healthcare applications

Gaslini Institute, Genoa - CMV pp65 protein Ag recognized by CD4 cells induced with immunodominant peptides

GeneGo, Inc. - Systems biology company adds Bristol-Myers Squibb to customer base

Genentech - Cancer drug Avastin use increases risk of stroke, heart attack

German Cancer Research Center - Computer simulation models the response of tumors to radiotherapy

GlaxoSmithKline Pharmaceuticals - Guinea pig 5-ht5A receptor characterized

Guilford Pharmaceuticals Inc. - Clinical trials to determine optimal Aggrastat therapy for PCI patients

Harvard University - Higher consumption of sweetened beverages associated with obesity, diabetes

Harvard University - Increases in body weight and abdominal fat raise diabetes risk

Hay Group - Study finds medical premiums continue double-digit to rise

Health Protection Agency, London - Meningococcal conjugate vaccine loses effectiveness after 1 year

HealthEquity, Inc. - Health savings account company adds director of corporate development

IMCOR Pharmaceutical Co. - Brian M. Gallagher, PhD, and Darlene M. Deptula-Hicks named to board

Illinois Council on Developmental, Disabilities - Developmental disabilities council chairperson named

Imperial College London - E-mail consultations could improve health care delivery, claim researchers

Information Technology - Beverly Hills Pharmacy gets a robotic hand in prescription filling

Instituto Butantan - Adjuvant improves protection induced by vaccine against N. meningitidis

Int. Center for Genetic Engineering and Biotech. - Hepatitis E virus protein regulates extracellular kinases

Integrated Healthcare, Systems, Inc. - Pharmacy automated equipment and software provider adds VP of customer service

Invitrogen Corp. - Life science technology company affirms $200M share repurchase program

Isis Pharmaceuticals, Inc. - Antisense drug demonstrates significant durable reductions in cholesterol

Johannes-Gutenberg-University - Immunotherapy of cancer reviewed

Johns Hopkins Medical Inst. - Intraurethral MRI can help assess female urethral sphincter deficiency

Johns Hopkins Medical Inst. - New DNA vaccine targets proteins expressed in cervical cancer cells

Johns Hopkins University - "Self-recovery" from liver infection linked to genes

Kaplan Medical Center - L1-based diagnosis, prognosis may improve ovarian, endometrial cancer management

Keio University - Non-invasive elastometry is a valuable tool for staging liver fibrosis

Kurihama National Hospital - Serotonin transporter gene is associated with anorexia nervosa

Kyoritsu College of Pharmacy - FAK upregulates antioxidant enzymes in transfected leukemic cells

Kyungpook National University Hospital - Diverse clinical applications using advantages of allogeneic PBL SCT

Leicester Royal Infirmary - Antiangiogenic agents are important adjuncts to conventional chemotherapy

Leiner Health Products Inc. - Pharmaceutical company reports increase in first quarter 2005 sales

Limerick Regional Hospital - Novel cross-wiring technique is descibed for fractures of the humerus in children

Lumenis Ltd. - Medical device manufacturer announces settlement of patent litigation

Lung Cancer - FDA approves lung cancer drug

M.D. Anderson Cancer Center - Circulating tumor cells in blood indicate more aggressive disease

Maccabi Health Service, Tel Aviv - AGUS coexisting with ASCUS signals clinically significant pathology

Mario Negri Inst. for Pharmacological Research - Data linking B-cell non-Hodgkin lymphoma to hepatitis C is inconclusive

Matritech, Inc. - New web site launched for online orders of NMP22 BladderChek Test

Mayo Clinic - Large-volume paracentesis can be performed safely as an outpatient procedure

Mayo Clinic - Researcher uses supercomputer to model a SARS viral enzyme

Med-Design Corporation - Safety needle producer reports preliminary second quarter financial results

MedImmune, Inc. - Curative Health Services renews contract for Synagis

MedPointe Pharmaceuticals - Astelin effective in patients who responded unsatisfactorily to Allegra

Medical College of Wisonsin - Test for diagnosing spread of melanoma can spare second operation

Merix Bioscience - Therapeutic immunotherapy vaccine manufacturer announces new leadership

Mesa Laboratories, Inc. - Electronic instrument manufacturer reports increased sales in first quarter

Metabolon, Inc. - Biomarker study to identify unique metabolic signatures for ALS

Milestone Scientific Inc. - Anesthetic delivery systems manufacturer announces operating results

Millennium Biotechnologies, Inc. - Resurgex nutritional formula beneficial for HIV patients on HAART therapy

Morphotek Inc. - Biotechnology company selects contract manufacturer for therapeutic antibody

Mpex Pharmaceuticals, Inc. - IND filed for clinical trial to study aerosol candidate in cystic fibrosis

NPS Pharmaceuticals, Inc. - Promotion agreement announced for Kineret rheumatoid arthritis therapy

NanoString Technologies, Inc. - Nanotechnology company raises $4.3 million in early stage capital

National Institute Environmental Studies - Nitrogen dioxide air pollution is atherogenic risk in obese subjects

National Scientific Research Center, France - New antimalarial compound identified through behavior of wild chimps

National University System - University system announces formation of California Medical Institute

Natl. Inst. of Biol. Stds. & Cntls, Hertfordshire - European union regulations for vaccine adjuvants and delivery systems listed

Natl. Inst. of Biol. Stds. & Cntls, Hertfordshire - Subcutaneous immunization allows uptake of diphtheria vaccine

Neose Technologies, Inc. - Protein therapeutics company reports second quarter financial results

Nestec Ltd - Activity of E. coli phages have implications for phage therapy

New York University - Second-generation antipsychotic agents increase diabetes risk

NewMarket Technology, Inc. - Technology company announces second quarter financial results

Newcastle Mater Misericordiae Hospital - Spiders given a bad rap

NitroMed, Inc - Pharma company reports successful results for the second quarter 2004

Northwestern University - S100B overexpression augments ischemic neurological damage

Nostrum Pharmaceuticals, Inc. - Elite Pharmaceuticals announces end of merger negotiations

Novo Nordisk - Healthcare company focusing on diabetes care announces financial results

Nuvelo, Inc. - Pharmaceutical company announces second quarter 2004 financial results

OXIS International, Inc. - Drug development company reports second quarter financial results

Ohio State University - New eating disorders model includes personal, sociocultural, and relational variables

Oita University - Molecular analysis of Plasmodium ovale variants reported

Optive Research, Inc. - Contracts signed for drug discovery software at tradeshow

Oscient Pharmaceuticals Corporation - Biopharmaceutical company announces financial results

OsteoBiology Inc. - Handheld probe is useful for detecting degenerative changes in joints

Pamel Vision and Laser Group - Lens implant study in final stages of FDA approval, company recruits patients

ParadigmHealth - Disease management company demonstrates compliance with national standards

Peninsula Medical School, Plymouth - School run does not affect children's activity levels

Penn. Health Care Cost Containment Council - Gastric bypass surgeries in Pennsylvania increase 10-fold in 5 years

Phyt-Immum GmbH - Pollen-blocking cream may help reduce allergy symptoms

Portola, Pharmaceuticals Inc. - Pharmaceutical company names executive vice president

Prince Songkla University - Biodegradable composite shows promise as antibiotic delivery system

Private Healthcare Systems - Tallahassee Memorial Healthcare added to PPO network

Prostate Cancer - Radiation plus short-term hormone drugs improve prostate cancer

Questcor Pharmaceuticals, Inc. - Pharmaceutical company announces 41% second quarter revenue increase

RIKEN Brain Science Institute - Virus-specific properties encourage brain cell gene transfer

Referral System - MedManage Systems launches online drug-sampling platform on Doctordirectory.com

Rockwell Medical Technologies, Inc. - Medical technology company reports significant second quarter improvements

Royal College of Surgeons of England - Publishing surgeons' performance remains controversial

Royal Free University of College London - Method for widespread application of adoptive transfer of virus-specific T cells

Rush University - Researchers focus on genetic mutations in autonomic nervous system

Rutgers State University - Transporters play significant role in absorption and disposition of drugs

SHARED - Organization committed to improving access to medicines names board members

SOLA International - Optical lens maker reports net sales increase in first quarter 2005

Safety Syringes, Inc. - Companies collaborate to provide needle safety for 2004 season flu vaccine

Salmon of the Americas - Salmon study shows levels of PBDEs pose little risk

Schering AG - Jenapharm's therapeutics business sold to Dermapharm AG

Schick Technologies, Inc. - Medical device company reports net revenues up in fiscal 2005 first quarter

Sentillion - Hospital group picks system to drive board of pharmacy authentication compliance

Seoul National University - Genetic adjuvants enhance efficacy of vaccine against Her-2/neu tumor antigen

Seoul National University - NA and PB1 genes of H1N2 influenza A virus from pig is of human origin

Sexually Transmitted Disease - Arizona State University receives federal grant for STD drug research

Shanghai Jiao Tong University - Surface topography cues affect cell characteristics

Shire Pharmaceuticals Group Plc - FDA approves adult attention deficit hyperactivity disorder drug

Simon Fraser University, British Columbia - Web server provides pipeline for microarray data

SkyePharma PLC - Pharmaceutical developer receives $5 million for transfer of skin gel rights

Smith & Nephew - Orthopedics company names Ken Woody senior VP for global sales

Sontra Medical Corp. - Fear of needles could become a thing of the past.

St. Bart. & Royal London Schl of Med. & Dent. - Plasmid encoding H. pylori urease induces specific antibody response

St. James's University Hospital, West Yorkshire - Hypertonic saline-induced sputum and cough swab samples have clinical value

St. Joseph Hospital - California hospital opens interactive health education exhibit at Disneyland

State Univ. of New York, Buffalo - Four resistance factors identified in interferon inhibitory activity

State University of Ghent Hospital - The dynamics of Tc-99m-HYNIC annexin V uptake vary in head and neck cancer

StemCyte, Inc. - Cord blood banking company surpasses 100th unit for stem cell transplant

Sungkyunkwan University - Rapid Down syndrome diagnosis available with QF-PCR

Sunnybrook & Wom. Coll. Hlth Sci. Cntr, Toronto - Soluble growth factor receptor is a major biomarker for angiogenesis

Swedish Cancer Registry - Period analysis provides up-to-date long-term cancer survival estimates

Synovis Life Technologies, Inc. - Cardiac rhythm device maker appoints Richard W. Kramp president, COO

Syst. Neuromodulateurs des Comportements Ingestifs - Ghrelin plays role in obesity development outside of leptin signaling

Tempus Software - Louisiana hospital installs software scheduling system

The Sugar Association - Study linking sucrose and breast cancer questioned by sugar trade organization

ThinkEquity Partners - Stuart Pulvirent to head healthcare research group for investment firm

Tohoku University - Expression of EBAG9/RCAS1 is associated with advanced disease

Tokyo Institute of Technology - Hrs regulates the sorting of growth factor receptors on early endosomes

Transgenomic Inc. - Biosystems research company reports second quarter and year-to-date 2004 results

Trimedyne Inc. - Surgical laser maker reports revenues for quarter, 9 months ended June 30, 2004

Tufts University - CodY is activated by direct interaction with branched-chain amino acids

Tufts University - Role of age in phenacetin and chlorzoxazone biotransformation determined

Type 2 Diabetes - Symposium addresses role of chromium in insulin resistance

U.S. Centers for Disease Control and Prevention - Economic cost of fatal occupational injuries in the U.S. reported

U.S. Food & Drug Administration - Autoclave sterilization produces acrylamide in rodent diets

U.S. National Cancer Institute - BRM/BRG1 expression has prognostic value in NSCLC

U.S. National Institutes of Health - Online resource is created for definition of BLAST search strategies

UCI Medical Affiliates, Inc. - Medical center management company reports third quarter fiscal year 2004 results

Univ. of Illinois, Urbana-Champaign - Enzyme activation appears key in helping internal clock tell night from day

Univ. of Texas Medical Branch - Oligonucleotide decoys modulate trauma response in the nervous system

Univ. of Texas, Dallas - Rare mutations can significantly increase risk factor for heart disease

University College London - Mutation at position 129 of prion protein doesn't affect its cellular form

University College of London - Drug users who are HCV-seronegative may be positive for RNA

University Hospital Liege - Malignant melanomas increasing in teenagers and young adults

University Medical Center Rotterdam - Colony blot assay useful for detection of multiple pneumococcal serotypes

University of Alabama - Strategies for managing suspected plague cases outlined

University of Birmingham - Gene-deleted oncolytic adenovirus vector activates cancer therapy

University of Cambridge - Bcl-2 antisense nucleotide sensitizes interferon-resistant renal cancer to Fas

University of Cincinnati - Certain dietary supplements pose a threat to liver transplant patients

University of Colorado - Pre- and perinatal factors affect risk of islet autoimmunity in early childhood

University of Copenhagen - Nerve stimulation ineffective against intractable interstitial cystitis

University of Dortmund - DNA-directed immobilization improves antibody microarray performance

University of Firenze - Static magnetic field exposure limits angiogenesis in laboratory assays

University of Florence - Infarct size and severity correlate with left ventricular ejection fraction

University of Genoa - Patients with renal dysfunction have a high cardiovascular mortality

University of Heidelberg - Simple procedures preserve bone marrow mRNA and gene expression patterns

University of Kentucky - Nucleophosmin partners with nuclear factor-kappa B to activate the SOD2 gene

University of Leeds - Innovative ceramic-on-metal hip replacements to undergo clinical trials

University of London - Glycosylation system is important for attachment to epithelial cells

University of London Imperial College Science and - Toll-like receptor 4 contributes to efficient control of Leishmania growth

University of Maryland - Immuno-PCR for HIV-1 p24 antigen lowers HIV-1 viral load detection limits

University of Michigan - Chemo-radiation offers better post-treatment voice quality for laryngeal cancer

University of Michigan - Parents' anti-asthma efforts may miss the mark

University of Minnesota - Gene associated with lupus identified

University of Minnesota - PEG-coated Si(111) surface improves protein immobilization

University of Missouri-Columbia - Intermittent exercise better than continuous

University of Modena & Reggio Emilia - Red wine prevents vascular oxidative stress induced by high-fat meal

University of Nottingham - COX2 inhibitor could offer benefits over other anti-inflammatory drugs

University of Nottingham - Small delay in delivery does not worsen problems for very premature babies

University of Palermo - Lymphadenopathy can't predict how hepatitis C will respond to antivirals

University of Pennsylvania - Massage therapists have high prevalence of hand dermatitis

University of Pittsburgh - Effects of carbon fiber microelectrodes on brain tissue determined

University of Pittsburgh - MDs have more influence on quitting smoking than other healthcare providers

University of Pittsburgh - Prenatal marijuana and alcohol exposure negatively affects later academic skills

University of Poitiers - Forced dystrophin expression improves calcium handling in muscle cells

University of Queensland - Dendritic cells and Langerhans cells both cross-prime T cells

University of Reading - Training techniques may enhance the lives of people with PD

University of Sao Paulo - Vaccine adjuvants play vital role in vaccine efficacy

University of Southern California - Lipid rafts protect hepatitis C virus replication complexes

University of Sydney - New screening technologies need further evaluation

University of Tokyo - Novel PDZK4 gene upregulated in SS tumor cells

University of Tokyo - RRF disassembles the ribosomal complex independently of EF-G

University of Tubingen - Differential gene expression identified in UCH-L1-deficient mice

University of Tubingen - New methods may improve management of late CMV infection following SCT

University of Tubingen - Tumor vascularity is a major player in cutaneous melanoma progression

University of Twente - Bubble-driven microfluidic transport is cheap and parallelizable

University of Utah - Endothelin-1 regulates systemic blood pressure, renal sodium excretion

University of Verona - dGK gene analysis should be performed on infants with cirrhosis

University of Washington - HIV protease inhibitors are inhibitors but not substrates of BCRP/ABCG2

University of Western Australia - Researchers: new paradigm needed for asthma drug-development strategies

University of Western Ontario - Understanding of poxvirus pathogenesis advanced by deleting viral genes

University of Wyoming -  C. elegans genes involved in pharyngeal development identified

Upstate Medical University, Syracuse - Early cementing doesn't raise debond energy of grit-blasted interfaces

Valeant Pharmaceuticals - Pharmaceuticals company announces filing of amendment to registration statement

Vanguard Health, Systems - Vanguard Health reports fourth quarter, fiscal year-end results

VantageMed Corporation - Healthcare software company announces 17% increase in revenue for Q2 2004

VaxGen Inc. - Biopharmaceutical company receives delisting notice from Nasdaq

Wake Forest University - Snake venom reveals clues about heart drug

Warner Chilcott PLC - Acne drug-focused company reports strong third quarter results ended June 2004

Washington University - BCNU promotes the death of oligodendroglioma-derived cells

West Nile Virus - West Nile may have been transmitted in Georgia dialysis center

William Beaumont Army Medical Center - Wood smoke increases expression of two mucin genes in rat airways

Yamanouchi Pharmaceutical Co. Ltd. - Novel antifungal compound derived from Phoma species

Yonsei Cardiovascular Center, Seoul - Overlapping stents are effective for long coronary lesions

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