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Lab Law Weekly

Susan Hasty, Publisher

Table of Contents . . . October 8th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Law Weekly | Other Publications

Applera Corp. - GTG reports on the current status of legal action to protect its patents

Business Update - Denver Health settles with nurses, union

Centers for Medicare & Medicaid Services - Most eligible hospitals are reporting quality-of-care data

Centers for Obesity Related Illness - Bariatric surgeons granted U.S. patent for gastric bypass surgical procedure

Chiron - Pharma announces settlement in HIV patent dispute with Roche

Drug Importation - Oak Creek, Wisconsin, mayor says he plans to veto Canadian drug proposal

Healthcare Costs - Study documents high markups on hospital charges

Legal Issues - Blue Cross Blue Shield sues Missoula, Montana's only radiology practice

Legal Issues - Lee Regional Health System sues Univ. of Pennsylvania Medical Center

Legal Issues - Self-insured surgeon sues Charleston Area Medical Center to keep privileges

Novartis - Pharma company wins Lamisil patent infringement lawsuit against Dr. Reddy's

Schering AG - Pharma company changes name of dermatology business to Intendis

U.S. Food and Drug Administration - FDA testing limits of medical technology

University of Kansas - High-tech pacifier being tested in hospitals may help preemies

Aarhus University Hospital - Perinatal factors could program an individual for risk of cardiovascular disease

Acusphere, Inc. - Pharmaceutical firm elects Sandra Fenwick to board of directors

Adolor Corp. - FDA accepts Entereg (alvimopan) NDA for review

Advanced Stent Technologies - FDA conditional approval granted to use Petal Stent System in BOSS trial

Ajou University - Tumor-specific gene therapy targets uterine cervical cancer

Akita University Hospital - Shiga toxin 1-neutralizing Fab fragment isolated

Albert Einstein College of Medicine - Parental vaccination beliefs in inner-city population described

Almond Board of California - Research shows almonds increase intake of several important nutrients

American Assn. of Oral & Maxillofacial Surgeons - Hazards of surgery and anesthesia for drug, alcohol abusers presented at meeting

Andrx Corporation - Pharmaceutical firm reports on meeting with FDA about manufacturing facilities

Aquagen International, Inc. - Financing agreement signed with HiProtech International

Assoc. of Clinical Research Org. - CRO group establishes global influence with Input to EMEA

Association of American Medical Colleges - Medical schools tighten conflict-of-interest standards

Bayer HealthCare Pharmaceuticals - Aprotinin injection during artery bypass graft surgery may reduce risk of stroke

Baylor College of Medicine - Calicivirus 3C-like proteinase inhibits cellular translation by PABP cleavage

Beijing Institute Transfusion Med - Mesenchymal stem cells can differentiate into retina-like structure

BioDelivery Sciences International - Biotech company announces $2,500,000 asset sale to Accentia

Biovail Corporation - Wellbutrin maker narrows revenue guidance

Brookdale University Hospital, Brooklyn - Alpha(v) integrin overexpression causes abnormal scarring

CSIC, Madrid - Endoglin plays a key role in cardiovascular development and vascular remodeling

California Institute of Technology - Fluorescent puromycin conjugates explore protein expression in vivo

Carrington Laboratories, Inc. - Biopharmaceutical firm's new marketing team to focus on product innovations

Celal Bayar University, Manisa - TGF-beta1 may be involved in the pathogenesis of chronic liver disease

Cell Therapeutics, Inc. - Oncology company to engage new independent audit firm

Cellegy Pharmaceuticals, Inc. - Interim results reported for phase II study using Tostrelle gel

Celsion Corp. - Cancer therapy company announces resignation of VP/medical director

Center Brasileiro Pesquisas Fis, Rio De Janeiro - Novel HIV glucosidase inhibitors developed with computer-aided technology

Centers for Medicare & Medicaid Services - Nursing home companies, QI groups, Medicare work together to reduce pain

China Pharmaceutical University - Anti-atherosclerosis polypeptide vaccine expressed in E. coli

Chinese PLA General Hospital, Beijing - Implanted stem cells tracked using radio-labeled transferrin scintigraphy

Chiron Corporation - Methods to monitor oligomeric state of HIV vaccine antigen evaluated

Chung Shan Medical University - Hibiscus flowers may prevent heart attacks

City Hospital - Controversies in managing osteomyelitis of the foot in diabetes reviewed

Columbia University - Molecular and cellular correlates mechanisms of ingestive behavior reported

CoreValve, SA - Medical-technology company establishes U.S. operations

Creighton University - VDR gene polymorphisms and bone loss rate association investigated

Cutting Edge Information - Study shows clinical trials last longer than expected

Cytovax Biotechnologies, Inc. - Biotech names Graham Strachan chairman of the board

Cytyc Corp. - Company licenses promising cancer detection technology from UMMS

Dana-Farber Cancer Institute - Chemokines linked to breast tumorigenesis

Diametrics Medical, Inc. - Diagnostics company announces new chairman of the board

EAS - Nutritional-products maker earns certification from NFL and NFLPA

Economic & Social Research Council - Is volunteering the blueprint for bliss?

Ecopia BioSciences, Inc. - Ecopia selects four new compounds for further profiling

Eli Lilly and Co. - FDA approves antidepressant Cymbalta for diabetic peripheral neuropathic pain

Eli Lilly and Company - Presentations of Exenatide show improvements in glucose control

Encysive Pharmaceuticals - Data on alternative for pulmonary arterial hypertension patients presented

Encysive Pharmaceuticals - Enrollment target reached for STRIDE-2, pivotal phase III trial for Thelin

Esaote - New factory opens in China to produce ultrasound scanners

Forbes Medi-Tech, Inc. - Company announces US$24.4 million in sterols sales agreement

Fox Chase Cancer Cntr. - Novel target found for detecting ovarian cancer in blood

Fujisawa Pharmaceutical Co. - Company updates the European development status of micafungin

Fukui University - Different calcium channel blockers exert different effects on MMP-2 expression

Genomic Society Consulting - Report: Drug-discovery technology is next offshore service

Georgia Institute of Technology - Heat-controlled drug implants offer hope for future

German Cancer Research Center - Environmental conditions in early childhood have long-term effect on immunity

Gifu University - Electroporation-mediated HGF gene transfer ameliorates pulmonary fibrosis

Guilford Pharmaceuticals Inc. - European marketing authorization issued for expanded use of Gliadel Wafer

Gunma University - Transplantation of pseudo-islets reverses hyperglycemia

Gynecologic Cancer - Gynecologic Cancer Foundation releases report on detection, treatment advances

Harvard University - Vaccine may be associated with increased risk of MS

Harvest Technologies Corp. - Company focuses on regenerative medicine, sells blood conservation technology

Health Discovery Corporation - Recently issued patent covers the use of support vector machines

Health Industries Research Companies - 2004 Employer and Coalition Service Profiles Supplement released

HealthAmerica and HealthAssurance - Managed care company names executive vice president of central Pennsylvania

Hennepin County Medical Center, Minneapolis - Time-integrated analysis should be used to examine all parameters concurrently

Hill-Rom Co. - Hillenbrand names Mark D. Ketchum and Eduardo R. Menasce to board

Hopital Albert Chenevier, Creteil - MRSA strains susceptible to aminoglycosides genotyped

Hospital Ramon y Cajal - Small bowel intraepithelial lymphocytes isolated using magnetic beads

Hungarian Academy of Science, Budapest - Noncommitted neuroectodermal SCs integrate into brain during tissue genesis

INSERM Unit 460, Paris - Knowledge of components of remodeling provide potential therapeutic targets

INSERM, Marseille - Patient-provider relationship must improve to increase long-term quality of life

Imaging Diagnostic Systems, Inc. - IDSI adds VP to commercialize laser mammography in global markets

Inst. de Invest. Biologicas Clemente Estable -  Proteus mirabilis structural fimbrial proteins elicit antibody response

Institute Butantan, Sao Paulo - Cholera toxin-pneumococcal surface adhesin fusion protein characterized

Institute of Cell & Molecular Medicine, London - Rashes from Oka vaccine are derived from single clones of virus

Institute of Tropical Medicine, Antwerp - HIV-affected families must deal with complex psychosocial issues

Instituto Nacional de Enfermedades Infecciosas - GRA4 or ROP2 protein partially protects against toxoplasmosis

IsoTis OrthoBiologics - OsSatura Dental receives 510(k) approval from U.S. FDA

Japan National Cancer Center, Kashiwa - Strong association of ARK5 with tumor invasion and metastasis

Jichi Medical School, Kawachigun - Myocytes with normal sinus rhythm were clearly differentiated

Kaiser Family Foundation - Private health insurance premiums rose 11.2% in 2004, survey shows

Kitasato University - Fungerin arrests cell cycle by inhibiting microtubule polymerization

Korea Food Research Institute - Flavonol glycosides from Eucommia ulmoides inhibit glycation

Korea University - Acidic polysaccharides may inhibit H. pylori adhesion to gastric cells

Kryotrans - "Intelligent" box can keep temperature stable for vaccine transport

Kyung Hee University - Adlay seed extract has hypolipidemic effects in obese rats

Lehigh University - Researchers quantify active Eustachian tube function

M.D. Anderson Cancer Center - Alemtuzumab may have a role in inducing important cardiac side effects

M.D. Anderson Cancer Center - Early intensive therapy beneficial for primary resistant myeloma patients

MTS Medication Technologies - Hurricanes delay company's relocation plans

Mashhad University of Medical Sciences - Leukocyte chromosomal DNA backs interferon production in Escherichia coli

Max Planck Institute of Molecular Genetics - Laboratory technologies converge to examine protein-DNA interactions

Mayo Clinic - Inflammatory marker may be early sign of blood vessel blockages

Mayo Clinic - Study finds risk of ADHD greater in boys

Mayo Clinic & Mayo Foundation - Epigallocatechin-3-gallate interrupts leukemia cell survival signals

Medical University of South Carolina - Retinol deficiency mars embryonic vessel growth by hindering angioblasts

Medline Industries, Inc. - HemoSense inks distribution agreement for point-of-care coagulation diagnostics

Mergers and Acquisitions - National Surgical Care acquires California-based multi-specialty surgery center

Micro Laboratories, Inc. - Oral spray vitamins manufacturer announces interim chief executive officer

Montpellier Univ. Hospital - Maintaining body weight in postmenopause protects against bone loss

Morehouse School of Medicine - HIV testing rate among African Americans not increasing due to low awareness

Morehouse School of Medicine, Atlanta - Traditional healers vital in AIDS prevention and control programs in Africa

MorphoSys, AG - Crucell and DSM announce PER.C6 licensing agreement for antibody production

Multiple Myeloma Research Foundation - CDC awards grant to fund blood cancer education program

Nantong Medical College, Jiangsu - Running peripheral sutures increase strength of oblique tendon repairs

National Cancer Institute - Expression of telomerase RNA template is limiting

National Institute of Immunology, New Delhi - Microparticle encephalitis vaccine elicits mixed immmune response

National Water Research Institute Branch, Saskatoo - Nickel may affect structure and function of river biofilm communities

Neurocrine Biosciences, Inc. - Positive results reported from Indiplon trial in elderly insomnia patients

New York State Department of Health - Novel cell lines identified for SARS-CoV diagnostics or basic research

NexMed, Inc. - Drug delivery technology company announces upcoming presentations

Nihon University - Cone-beam CT system facilitates maxillary implant treatment

North Carolina State University - Clone of L. monocytogenes serotype 4b implicated in food-borne listeriosis

North Carolina State University - Immunization with Listeria controls virus load after FIV challenge

Nucryst Pharmaceuticals Corp. - Phase 2a trial results reported for investigational drug in atopic dermatitis

Observatoire Regional de la Sante, Marseilles - IVDA cessation concomitant with decrease in other addictions and unsafe sex

Ophtec, BV - Friesland Bank obtains minority interest in Dutch company

Organica Biotech - Biotech company picked to purify Philadelphia's infamous odor

Orion Pharma - Pharma companies launch Parkinson disease study

Osped Riuniti, Reggio Di Calabria - Interventions to curb CV mortality of ESRD should target hypertension and LVH

Osteoporosis - Soy isoflavone + moderate exercise prevents increased body fat, bone loss

PURE Bioscience - Bioscience company supports national food safety education month

Pain Therapeutics, Inc. - Biopharmaceutical company completes phase III enrollment for low back pain study

Peking University - Lysophosphatidic acid stimulates the adventitia to produce adrenomedullin

PerkinElmer Inc. - Predictive Diagnostics partners to advance biomarker discovery

Peter MacCallum Cancer Institute, Victoria - Gene-engineered T cells are superior adjuvant therapy for cancer

Pfizer Inc. - Sulfonylurea and phosphodiesterase inhibitors increase insulin secretion

PharmaLinkFHI, Inc. - eClinical research organization expands business development team

Pharmacia Diagnostics AB - Two-thirds of prescription antihistamine users test negative for allergies

Procter & Gamble - Trick-or-Treat for UNICEF campaign 2004 to help children in Latin America

Prostate Cancer Foundation - Foundation reports new partnerships for prostate cancer awareness month

Public Interest Watch - Public interest group calls for investigation of communications contract

RIKEN CDB Laboratory - New mechanism discovered in the regulation of mesenchymal-epithelial transitions

Rensselaer Polytechnic Institute - Sol gel-based electrochromatography chip developed

Rikshospitalet University Hospital - RelB mediates TNF-induced up-regulation of polymeric Ig receptor

Riverkeeper - Study predicts human damages from Indian Point nuclear plant terror attack

Rosalind Franklin University of Medicine & Science - Techniques for debriding and off-loading diabetic foot wounds described

Roskamp Institute - Murine cerebral amyloidosis models exhibit impaired vascular formation

Royal Free & Univ. College Med. School, London - Recruiting London gay men into HIV vaccine trial is feasible

Rush Medical College - Antiretroviral therapy is safe for women with HCV infection

Schering AG - Bonefos accepted for filing and granted priority review by FDA

Second Military Medical College, Shanghai - A strategy of combining antiangiogenesis with oncolysis eradicates cancer

Seoul National University - Genomic effects of AzaC and dioxin characterized

Seoul National University - Risk factors identified for low BMD of calcaneus, distal radius in Korean group

Seoul National University Hospital - Cyst fluid analysis useful for differential diagnosis of pancreatic cysts

Smith & Nephew Endoscopy - Joint-specific instruments provide better arthroscopic access to the hip

Solbec Pharmaceuticals Ltd - Pharma company finds anticancer drug effective in reducing tumor size

Somaxon Pharmaceuticals, Inc. - Pharmaceutical company appoints vice president clinical development

St. Croix Medical, Inc. - Clinical studies phase for hearing implant device started in U.S. and Germany

St. John's University, Jamaica - Screening test modified to identify herbals with sulfonylurea-like activity

St. Jude Children's Hospital - Understanding biology of AT can lead to greater knowledge of its underlying processes

Stanford University - Glycan arrays lead to discovery of autoimmunogenic activity of SARS-CoV

Stanford University - Marijuana-like chemicals in the brain calm neurons

Stanford University Medical Center - PSA era is over for predicting prostate cancer risk, say Stanford researchers

State University of New Jersey - Splitting muscle relaxant could cause inconsistent dosing, unpredictable relief

Stereotaxis, Inc. - Cardiology device maker announces underwriters' exercise of optional shares

Strakan/ProSkelia - Wilson Totten appointed CEO of merged, re-named pharmaceutical company

Sungkyunkwan University - C-reactive protein raises heart disease risk by impairing angiogenic function

Surgery Specialties - Colorectal neoplasm preoperative tattooing reliable for laparoscopic resection

Surgical Information Systems - Surgical company recognized as leader in customer satisfaction

Syngenta - Diversa gets milestone payments for identifying protein therapeutic candidates

Synthes, Inc. - U.S. FDA approves expandable prosthetic titanium rib for children with TIS

Tercica, Inc. - Hormonal cause of short stature linked to insulin-like primary IGFD, study shows

Teva Neuroscience, Inc. - Agilect reduced tremor and severity of "off" time in Parkinson patients

Texas Children's Hospital, Houston - Serial surveillance of patients is vital after arterial switch operation

The Procter & Gamble Company - Consumer products company confirms first quarter guidance

The Wistar Institute - Genetic suppressor elements offer a new approach for treating rabies virus

TheraQuest Biosciences - Discovery of analgesic that increases potency of morphine announced

Tianjin University -  Ligusticum chuanxiong and Angelica sinensis protect ECV304 cells

Tobacco Use - Smoking results in low plasma levels of vitamin C in mother and newborn

Tokyo Medical & Dental University - Ligands for ICOS potentially suppress HIV-1 replication mainly at entry stages

Tokyo Rinkai Hospital - Increased adenosine primary factor for hyperuricemia in twin pregnancies

Tufts University - Policies and consequences related to obesity in the U.S. reviewed

Tulane University - Effects of chronic hypoxia are described

Twenteborg Hospital, Almelo - Multidisciplinary approach optimizes surgical therapy of diabetic feet

U.K. Health Protection Agency, London - Norovirus gastroenteritis longer in healthcare settings than in healthy persons

U.S. Department of Veterans Affairs - New software adopted by veterans group to improve process of informed consent

U.S. Food & Drug Administration - Expanded family of class II cytokines share IL-10 receptor-2 (IL-10R2) chain

U.S. Food and Drug Administration - Panel urges child antidepressants warning

U.S. National Institutes of Health - NOD2 is negative regulator of Toll-like receptor-mediated T helper responses

U.S. Natl. Cancer Institute - Development of therapeutic nucleic acids is ongoing

UICI - Insurance company announces execution of agreement to acquire HealthMarket, Inc.

UnitedHealth Group - Gregory A. Arms appointed senior vice president of healthcare services company

Univ. of California, Davis - Plasma selenium decrease in pregnancy associated with glucose intolerance

Univ. of California, Los Angeles - Substance abuse programs would slow HCV transmissions among homeless men

Univ. of California, San Francisco - Chronic stress promotes palatable feeding and reduces signs of stress

Univ. of California, San Francisco - Molecule awakens and maintains neural connections

Univ. of California, San Francisco - Older women with heart disease, diabetes have triple the risk of heart failure

Univ. of Texas Health Science Center, San Antonio - Robotically positioned transcranial magnetic stimulation system is accurate

Universitat de Lleida - AIDS progression linked to Fok-I polymorphism of VDR gene

University Hospital, Pisa - Oxygen supplementation seems to be a promising treatment

University Hospital, Strasbourg - Vascular grafting is effective in revascularization

University Medical Centre, Utrecht - Simple technique devised for tracheo-esophageal fistula closure

University of Alberta, Edmonton - Bispecific monoclonal antibody detects causative agent of whooping cough

University of Athens - Efficacy of total hip arthroplasty for hip osteonecrosis reviewed

University of Bologna - Study: Oocyte cryopreservation is a biologically "realistic objective"

University of British Columbia - Researchers aim to create "living glue" for replacement joints

University of Cape Town - Anticipatory response ensures that thermal homeostasis is maintained

University of Central Florida - Bacteria may be at root of Crohn disease

University of Chicago - Germ study suggests bloodletting may work

University of Chile - Inhalation of particular matter can increase cardiovascular disease incidence

University of Colorado - Potential approaches to problems of critical limb ischemia are discussed

University of Connecticut - Morbidity from repeated tracheal intubation characterized

University of Dusseldorf - Network properties of teratocarcinoma cell line-derived neurons determined

University of Ferrara - Defective CD34+ progenitors compromise myelodysplastic syndrome therapy

University of Florida - Authors review cases of cardiothoracic surgery performed on Jehovah's Witnesses

University of Frankfurt - Use of regional anesthesia in orthopedics reviewed

University of Genoa - New assay for antigenic characterization influenza B virus developed

University of Glasgow - Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase screened

University of Groningen - The Na+-citrate transporter CitS of K. pneumoniae has a pore loop structure

University of Heidelberg - Combination of amphotericin B formulations improves efficacy

University of Leeds - Swing phase loads affect wear of metal-on-metal hip implants

University of Lund Hospital - Maternal schizophrenia and affective psychoses affects offspring's development

University of Mainz - No evidence reported for phospholipase D activation by GI or IPC

University of Maryland - Pathways provide phenotypes useful in treating defects of galactose assimilation

University of Maryland - Radiation spawns genomic instability through cytokine induction

University of Miami - BMP signaling initiates neural crest differentiation in embryonic CNS stem cells

University of Nevada Reno - Fetal sheep model assesses full differentiative potential of human stem cells

University of New Mexico - Prolonged and frequent dialysis permits better control of hypertension

University of North Carolina - Novel podophyllotoxin derivatives have anti-HIV activity

University of Otago - Cell-specific betaC-activin expression characterized

University of Pennsylvania - 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites

University of Pennsylvania - Quality of CD8+ T-cell memory is important

University of Pittsburgh - Biologic therapy for brain cancers reviewed

University of Saarlandes Kliniken - EBV, CMV in synovial tissue determined by RNA-, DNA-in situ hybridization

University of Sao Paulo - Medial prefrontal cortex has excitatory action on the sympathetic nervous system

University of Texas - The flagellar motor controls exopolysaccharide expression in V. cholerae

University of Tokyo - Changes in rats correspond to changes relevant to CV diseases in humans

University of Tokyo - Mild exercise training does not increase MCT4; causes complex changes in MCT1

University of Utah - U.S. patent for rapid nucleic acid amplification awarded to university

University of Vale do Itajai - Brazilian herbal medicines reduce weight gain or cholesterol levels

University of Virginia - Phosphorylation alters Xenopus Ca-activated Cl currents

University of Virginia - Protein scaffolds guide capillary sprouting using an elastic fiber matrix

University of Wales - Wound dressings for diabetic foot disease reviewed

University of Wisconsin - Dendritic cell-based immunotherapy for cancer reviewed

University of Wurzburg - False aneurysm of the lateral superior genicular artery reported

Uppsala University -  Anopheles malaria mosquitoes increase in relation to housing conditions

Valentis, Inc. - Schering AG pays $1 million option license fee to cardio-focused company

Vanderbilt University - Roles of IgA and IgG in influenza control in respiratory tract studied

Vanguard Health Systems - Acute care hospital firm offers senior subordinated notes, senior discount notes

Vasomedical, Inc. - Benefits of EECP therapy for heart disease presented

Verispan - Healthcare information provider offers managed-care focused primary research

Victoria University of Wellington - Peloruside A tubulin binding characterized

Vienna Medical University - RNA inhibition counteracts the growth of human mammary tumor xenografts

Virginia State Department of Health - Virginia State Health Department gets $20 million

Vita Salute University - The serotonin transporter gene does not link carbon dioxide to panic disorder

Washington State University - Androgen-responsive genes blanket the epididymis

WellPoint Health Networks - New Health Plan NCQA Accreditation awarded to Unicare for Medicaid business

West Penn Allegheny Health System - Health system to transition Suburban General Hospital to northern campus of AGH

Xiamen University - Novel immunogenic proteins of Shigella flexneri identified

YMCA of the USA - Local leaders, national experts 'activated' to combat obesity, chronic diseases

Yale University - Gambling linked to good health in elderly

Yale University - HVS Orf51 protein has role in viral pathogenicity/persistence/cell tropism

Yale University - Study describes predictors of outcome of myocarditis in pediatric patients

Zix Corporation - Tennessee healthcare company selects provider of HIPAA secure e-services

Zonagen, Inc. - Zonagen Stock to Trade on NASDAQ Small Cap Market

ZymoGenetics, Inc. - Douglas E. Williams named executive VP, chief scientific officer by biotech firm

ZymoGenetics, Inc. - James Harper appointed to board of directors of pharmaceutical company

ZymoGenetics, Inc. - Strategic biopharm research, development and commercialization alliance formed

aaiPharma Inc. - Pharmaceutical company regains NASDAQ listing compliance

ev3 Inc. - Companies announce strategic distribution alliance

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