Published in Lab Law Weekly, October 29th, 2004
"Intervillous blood flow increases after 10 weeks of gestation and results in exposure of trophoblast cells to oxygen. Before this time, low oxygen appears to prevent trophoblast differentiation toward an invasive phenotype," wrote H. Nishi and colleagues.
"The oxygen-regulated early events of trophoblast differentiation are mediated by transforming growth factor (TGF)-beta3. TGF-beta3 plays a vital role in trophoblast differentiation, and its overexpression can be...
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