Published in Lab Law Weekly, October 29th, 2004
"Grapefruit juice can modify the pharmacokinetic parameters of many drugs, in particular simvastatin, an orally active cholesterol-lowering agent," pharmacologists in France explained. "The exact components in grapefruit juice responsible for drug interactions are not perfectly known."
"However, it seems that bergamottin, a furocoumarin derivative, is one of the main active components within grapefruit juice," noted N. Le Goff-Klein and colleagues at Louis Pasteur University. They conducted a study "to quantify and to characterize in vitro the inhibitory effect of...
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