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Medarex, Inc.

Pharma companies enter into research agreement on antibody product

Published in Lab Law Weekly, June 10th, 2005

Ono Pharmaceutical Co., Ltd., and Medarex, Inc., (MEDX) announced that they have entered into a collaborative research agreement to research and develop a fully human antiPD-1 antibody for the potential treatment of cancer.

The parties have already started generating fully human antiPD-1 antibody product candidates under Ono's intellectual property regarding PD-1 and using Medarex's proprietary UltiMAb Human Antibody Development System, and they expect that clinical studies could begin in 12 to 24 months.

Under this arrangement, Ono and Medarex will jointly work toward potential commercialization of an antiPD-1 antibody. The two companies plan to...

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