University of Fed Santa Maria

Humoral response against LMW antigens important for detection of latent TB

Published in Lab Law Weekly, August 19th, 2005

The humoral response against low molecular weight antigens is important for the detection of latent tuberculosis.

"Much effort has been devoted to the identification of immunologically important antigens of Mycobacterium tuberculosis and to the combination of target antigens to which antibodies from serum of tuberculous patients could react specifically.

"We searched for IgG antibodies specific for antigens of 45 to 6 kDa obtained after sonication of the well-characterized wild M. tuberculosis strain in order to detect differences in the antibody response to low molecular weight antigens from M. tuberculosis between patients with...

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Source: Lab Law Weekly (2005-08-19)

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