Boston University

Three papers present fresh paths to ponder Akt1 in the heart

Published in Lab Law Weekly, August 19th, 2005

Akt is a molecule involved in many cellular functions, including growth, survival and metabolism. Akt exists in three isoforms - Akt1, Akt2 and Akt3 - which have a substantial degree of functional overlap.

In the heart and vasculature, Akt may be protective against ischemia and it may enhance cardiac function after heart failure. But Akt may also have detrimental effects.

In its August 1, 2005, issue, the Journal of Clinical Investigation presented three research papers that explore Akt1 in the heart, plus an accompanying commentary. The first paper, by Anthony Rosenzweig and colleagues at Harvard, and the second paper by Kenneth Walsh and...

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Source: Lab Law Weekly (2005-08-19)

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