Lab Law Weekly

Nabi Biopharmaceuticals - Consistency lots study evaluates safety and immune response of investigational vaccine

Nagoya University - On-off switching of gene expression regulated with carbohydrate-lectin interaction

Nanjing Medical University - NORPEG expressed in human fetal testes, adult testes and spermatozoa

Nanogen, Inc. - Epoch Biosciences issued U.S. patent for detecting nucleic acid targets

National Cancer Center, Gyeonggi - Transcatheter arterial chemoembolization rarely aggravates hepatitis B-related liver disease

National Chiao Tung University, Hsinchu - Fe₃ O₄ /TiO₂ core/shell nanoparticles detect phosphopeptides levels of 500pM

National Sun Yat-Sen University, Kaohsiung - Statins can improve lipid profiles in patients with hyperlipidemia

National University of Ireland, University College Cork - Radial cells in the spinal cord are precursors to radial glia

NeoPharm, Inc. - Study results support feasibility of multimodality therapy for malignant glioma

Nigeria Federal Ministry of Health - Drug combination suppresses viral replication in HIV/AIDS patients in Nigeria

Nizam's Institute of Medical Sciences, Andhra Pradesh - Sensitivity and specificity of rapid HIV test compared with fourth-generation ELISA

Northwick Park Hospital & Clinic Research Center, Harrow - Contrast echo can be used to detect coronary artery disease in patients presenting with heart failure

Novo Nordisk - E.U. approval received for premixed insulin analogues

OCG Technology, Inc. - Robert A. Shiver appointed president and CEO of PrimeCare Systems

OSI Pharmaceuticals, Inc. - Pharma company reiterates confidence in long-term prospects of Tarceva

OSI Systems, Inc. - U.S. FDA grants 510(k) approval for sale, distribution of anesthesia systems in U.S. market

Odense University Hospital - No survival benefit due to early initiation of adjuvant chemotherapy detected

Ohio State University - Urine adiponectin levels may be biomarker of renal systemic lupus erythematosus

Osiris Therapeutics, Inc. - Clearance granted for phase II trial of treatment for acute graft vs. host disease

Othera Pharmaceuticals, Inc. - Pharma company elects Hans Mueller to board

Ottawa General Hospital - Primary chemotherapy and debulking surgery advised for ovarian cancer management

Oxford BioMedica - Preliminary data shows renal cancer drug is safe and well tolerated

Oxford Ventures, Inc. - Holding company signs merger agreement to acquire Uluru

Polish Air Force Institute of Aviation Medicine - Decreases in antioxidative enzymes may play key role in artherogenesis

Princess Margaret Hospital, Toronto - Clinical trial recommended to further test combination of carboplatin and PLD

Provincial Laboratory for Public Health, Calgary - Focus and Panbio flavivirus enzyme immunoassays useful for diagnosis

Purdue University, West Lafayette - Early awareness might prevent avian flu pandemic

Purdue University, West Lafayette - Interdomain salt bridge in IGP synthase involved in mediating active site communication

Purdue University, West Lafayette - Nanophase ceramics increase osteoblast function

Pure Protein LLC - Competitive peptide-binding assay for HLA-A*0201 aids epitope discovery

Queen's University, Kingston - p21-activated kinase induces podosome formation in vascular smooth muscle cells

RAND Corporation - Many HIV-infected adults perceive discrimination by health care providers

Radboud University, Nijmegen - Model developed to evaluate inflammatory attacks in hyper-IgD syndrome

Raven Biotechnologies, Inc. - Biotech company raises $48.3 million for cancer research

Research Australia - Study gives young Australians with disabilities a healthy start

Research Triangle Institute - Letrozole provides longer time to disease progrssion when compared with tamoxifen

Royal Institute of Technology, Stockholm - High-throughput solubility assay for protein immunogens developed

Rural/Metro Corporation - Medical transport company announces $7 million unscheduled debt payment

SNBTS National Science Ltd. - MAIRA assay appears suitable for measurement of red blood cell markers during storage

Scott's Food & Pharmacy - Keltsch Pharmacy changes name to align identity with branding

Sectra Medical Systems - New PACS release optimized for very large data sets

Shiga University of Medical Science - Interleukin-22 induces inflammatory responses in colonic subepithelial myofibroblasts

Siga Technologies, Inc. - Smallpox vaccine effective against lethal doses of monkeypox virus

Skylight Healthcare Systems - Providence St. Peter Hospital to install interactive patient education system

Speedel Pharmaceuticals, Inc. - Phase 1 safety, tolerability testing of renin inhibitor for hypertension started

St. Jude Children's Research Hospital, Memphis - Ependymomas in other CNS locations appear to arise from radial glia cells

St. Jude Children's Research Hospital, Memphis - Retinoblastoma researchers demonstrate a new treatment with drug combination

State University of New York Downstate - Suppressed fibrinolysis found in obese adolescents with type 2 diabetes

Surface Logix - Biological microsystems developer appoints John Wm. Ferkany as vice president

Tarbiat Modarres University, Tehran - Low 5-year survival rate from gastric cancer attributed to delayed diagnosis

Tehran University of Medical Science - Cancer screening proposed for patients with family history of colorectal cancer

Temple University, Philadelphia - Angiocidin relies on polyubiquitin binding activity to generate apoptosis

Teva Pharmaceutical Industries Ltd. - Twenty-six year data support efficacy, safety of Copaxone in relapsing-remitting MS

Texas A&M University, College Station - Estrogen regulates contractile responses of female rat aorta to vasopressin

Texas Tech University - Study explores importance of relationship factors and safer sex practices

The Pharmaceutical Institute - Institute launches large library of pharma, biotech information, educational resources

Thomas Jefferson University, Philadelphia - Extracellular matrix formation can be altered by atypical fibronectin interaction

Threshold Pharmaceuticals - Pharmaceutical company announces follow-on offering of 6,250,000 common stock shares

Tokyo Medical & Dental University - Cyclosporin A blocks cyclophilins to suppress hepatitis C virus replication

Tokyo Medical University - Optical coherence tomography can detect early bronchial tumors

Tongji University, Shanghai - PLGA porous scaffolds are used to repair mandibular defects

U.S. Centers for Disease Control & Prevention - Method is developed to determine avidity for H. influenzae antibodies

U.S. National Cancer Institute - Development of histone deacetylase inhibitors as anticancer agents reviewed

U.S. National Institute of Allergy & Infectious Diseases - HIV vectors and molecular clones have similar neutralization phenotype

Universidad Autonoma de Madrid - Obesity and weight loss linked to high health service use among elderly

Universitatsklinikum Schleswig-Holstein, Lubeck - Doctors are advised to carefully assess causes of traumatic brain injury in children

Universite Mediterranee, Marseille - Activating killer immunoglobulin-like receptors recognize peptide-MHC class I complexes

University Clinic, Basel - Signs and symptoms are only moderately helpful in diagnosing CHF

University Hospital, Hamburg - Pulse contour-derived cardiac index accurate during changes of preload and aortic impedance

University Hospitals of Leicester - Researchers explore the potential chemopreventive roles of retinoids in cervical neoplasia

University Women's Hospital, Frankfort - Bendamustine prolongs progression-free survival in metastatic breast cancer

University of Aberdeen - Caspofungin and voriconazole combination has additive but not synergistic effects

University of Alabama - Genistein downregulates transcriptional and posttranslational MDM2 oncogene levels

University of Austral, Buenos Aires - Endothelin-1 and endothelin receptors are over-expressed in retinal degeneration

University of Barcelona - Major depression predicts higher mortality following stem cell transplantation

University of California, Los Angeles - Patients have increased hospitalization rates after gastric bypass surgery

University of California, San Diego - Visceral adipose tissue and type 2 diabetes highest among Filipino women

University of Cambridge - Maternity services should identify needs of nursing mothers to provide effective guidance

University of Cambridge - Sclerostin is an osteocytic product that inhibits bone formation

University of Chicago - Number of bariatric surgeries increased over 5-year period

University of Colorado - Melanoma inhibits macrophage activation by suppressing Toll-like receptor 4 signaling

University of Colorado School of Medicine - Colorado medical school identifies health challenges in Ghana and Peru

University of Edinburgh - Bovine tuberculosis detected in wildlife of northern Tanzania

University of Erlangen-Nurnberg - Select genotypes underlie cirrhosis progression in hereditary hemochromatosis

University of Florence - Intratumoral microvessel images shed light on ovarian cancer progression

University of Georgia - U.S. CDC awards $900,000 grant to study high school student behaviors

University of Hong Kong - Cigarette smoke extract uses angiogenic mediators to promote colon cancer growth

University of Houston - Targeted education affects women's knowledge and attitudes about breast cancer

University of Illinois - Emotional impairment linked to cognitive deficits in bipolar children

University of Illinois - Imidazenil antagonizes sedative but not anticonvulsant diazepam activity

University of Kansas - Telephone-based weight loss program can work, obesity researcher finds

University of Leipzig - Outcome of EERPE deemed on par with laparoscopic transperitoneal radical prostatectomy

University of Louisiana School of Pharmacy - Calcitonin boosts prostate cancer growth by stimulating intratumoral vascularization

University of Manitoba, Winnipeg - Approach provides means for assessing Na⁺/Ca²⁺ exchange ionic regulation

University of Melbourne - Mammographic density and bone mineral density unrelated to genetic determinants

University of Minnesota - Lower-dose topotecan tolerated in patients with pretreated ovarian cancer

University of Navarra - Molecular studies of colon cancer could contribute to more efficient treatment

University of Navarra - Perineuronal net destruction is caused by the pathogenic effect of prions

University of North Carolina - Risk of acquiring drug resistant HIV mutations is low for patients on HAART with detectable viremia

University of Oklahoma - Flex-Hets exhibit improved therapeutic ratios as anticancer agents over RAR agonists

University of Oporto - A neutral amino acid exchanger may be more densely distributed in renal porcine epithelial cells

University of Paris 05 - Circulating dendritic cells correlate inversely with HIV RNA and positively with CD4 cell counts

University of Pavia - Increased aldosterone may link depression to unfavorable vascular events

University of Pennsylvania - Local immune responses play major role in antibody formation to factor IX

University of Perugia - Balance between antioxidants and by-products of oxidative stress may be best stroke marker

University of Queensland - Queensland Brain Institute receives $650,000 spinal research bequest

University of Rochester Medical Center - Corticosteroids are often used in the treatment of infectious mononucleosis

University of Roma La Sapienza - Nation-based alcohol-drinking profiles associated with oral cancer mortality

University of Saskatchewan - Researchers able to predict a child's final adult height

University of Stellenbosch, Tygerberg - Recurrent tuberculosis in HIV-infected children common in high-burden TB setting

University of Sydney - Researchers propose HRT prescribing practices may impact breast cancer incidence

University of Texas SW Medical Center, Dallas - Texas researchers find alterations in brain's circuitry caused by cocaine

University of Texas, Austin - Duloxetine is new medication for treatment of major depressive disorder

University of Thessaly, Larisa - HCV-RNA transcription-mediated amplification detects infection in hemodialysis patients

University of Toronto - Pain scores look similar in patients given different liver biopsy procedures

University of Udine - Indications for marginal mandibulectomy identified

University of Udine - Review examines role of prothrombotic state and lipoprotein(a) as atherosclerotic risk factors

University of Ulsan College of Medicine, Seoul - Laparoscopic surgery declared effective alternative to laparotomy for cancer treatment

University of Ulsan, Seoul - Immobilization stress alters and causes oxidative damage in the nigrostriatal system

University of Ulsan, Seoul - Novel balloon sheath performs well in gastrointestinal phantom study

University of Ulster - Pipinin-1 from frog skin secretions is an insulin-releasing agent

University of Utah - Donor alcoholism and injection drug use don't affect graft survival

University of Utrecht - Bite force doesn't affect marginal bone loss in mandibular overdenture treatment

University of Utrecht - HemoCue glucose analyzer results are comparable with YSI glucose oxidase analyzer

Urigen Inc. - IND opened for phase 2b clinical trial with treatment for interstitial cystitis

Wake Forest University, Winston-Salem - Gamma knife is effective in treating trigeminal neuralgia

Washington Hospital Center - Cryoplasty effectively treats challenging peripheral artery blockages

Washington University, St. Louis - Vaginal brachytherapy recommended as sole treatment for stage IC endometrial cancer

Wellington Hospital, London - Varicose veins successfully treated once pelvic symptoms treated

Western University of Health Sciences, Pomona - First ketolide antimicrobial approved

World Health Organization - Youth suicide prevention approaches should address all disorders, not just depression

Wyeth Research - Novel potent and selective MMP-13 inhibitors synthesized

Xanthus Life Sciences - U.S. NCI awards $2.3 million to develop dosing technology for anticancer drugs

Xechem International, Inc. - Orphan drug status approved for sickle cell medicine in European Union

Yale University - Nonsynaptic GABAergic signaling exists between neuroblasts and GFAP-expressing cells

Yale University - Treatment effect of vitamin B-6 for depression not evident

Yonsei University, Seoul - Stent-assisted coil embolization effective for wide-necked aneurysms

Zhejiang University, Hangzhou - Fusion of myoblasts with myofibers provides efficient gene delivery

iCAD, Inc. - CAD imaging systems provider reports Q3 2005 revenue estimate at $3.4 million