Published in Lab Law Weekly, November 11th, 2005
"Flumazenil (FLU), a specific benzodiazepine (BZ) receptor antagonist, has been used in the treatment of acute BZ intoxication or the alleviation of BZ-induced withdrawal syndrome on the basis of its weak partial agonist action at GABAA receptors," pharmacologists in the United States explained. "However, given to patients, FLU can worsen diazepam-induced withdrawal syndrome by lowering seizure threshold."
J. Anta and colleagues at the University of Illinois "therefore investigated whether imidazenil, a selective positive allosteric modulator of GABA action at...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Lab Law Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.