Lab Law Weekly

Medical Oncology Service, Madrid - Recent findings in colon cancer described

Medical Research Council, Harwell - Nnt mutations uncouple beta cell mitochondrial metabolism leading to impaired insulin secretion

Medical University of South Carolina - Real-time 3D echocardiographic RV biopsy guidance feasible in children

MicroChem Lab, Inc. - Vinegar increases killing power of bleach

Miguel Hernandez University, Alicante - Disposable and nondisposable Moria M2 microkeratome heads produce similar flaps

Mount Sinai Medical Center, New York - University leaders in New York call for support of stem cell research

Mount Sinai School of Medicine, New York - Novel implant provides chronic sac pressure monitoring after endovascular AAA repair

Myogen, Inc. - Biopharma company announces sale of its European subsidiary, sublicenses rights to Perfan I.V.

NPS Pharmaceuticals, Inc. - Pharma company extends R&D alliance with AstraZeneca for GI drug development

Nanyang Technology University, Singapore - Reports advance knowledge in apoptosis research

National Cancer Institute, Aviano - New research in the area of lung cancer detailed

Neurobiological Technologies, Inc. - Drug development company reports net loss of $8,043,000

New York University Medical Center - IL-2/liposome potentiates immune responses to cancer vaccine

Numico Research BV - Researchers describe findings in neuroscience studies

Nutra Pharma Corp. - Robert A Ollar to act as chairman of Designer Diagnostics' scientific advisory board

ORTON Orthopedic Hospital, Helsinki - Cementless total hip arthroplasty effective for high congenital hip dislocation

OSI Systems, Inc. - Medical monitoring product developer announces record revenues of $117.1 million

Ohio State University - The redox environment affects wound healing

Okayama University - Interferon-ribavirin combination therapy is limited for older patients with chronic hepatitis C

Okayama University - Metaphase CGH useful for identifying chromosomal tumor alterations

Okayama University - p53 protein transduction therapy targets and inhibits bladder cancer cell growth

Orthop-disches Krankenhaus Gersthof, Vienna - Patients prefer one-stage bilateral hip replacement to two-stage procedure

Oscient Pharmaceuticals Corporation - Pharma company acquires expanded worldwide rights to Ramoplanin

PacificHealth Laboratories, Inc. - Nutrition technology company finds new soft chewable tablet reduces food intake by 20%

Parexel International Corporation - Perceptive Informatics announces release of clinical trial interactive web response system

Pennington Biomedical Research Center - New study finds chromium picolinate helps muscles use blood sugar

Pharmaceutical Institute - Institute to provide custom research services, access to databases and research reports

Pharming Group N.VConta - Biotech company signs partnership agreement with Paul Royalty Fund II, LP valued at US$30 million

Phytocon GmbH - A combined herbal preparation reduced cold symptoms and was well tolerated

Point Therapeutics - First patient enrolled in phase III clinical trial in metastatic non-small cell lung cancer

Policlin University, Messina - HBV-HCV co-infections are associated with a complex spectrum of virological profiles

Queen's Medical Research Institute, Midlothian - New findings in diabetes pathogenesis described

RIKEN, Kobe - Nuclear transfer embryonic stem cells improve cloning from somatic cells

Rabin Medical Center, Petah Tiqwa - Routine TB culture during bronchoscopy in nonendemic area is cost-effective

RehabCare Group, Inc. - Physical therapy provider elects Harry Rich to board of directors

Repligen Corporation - Biopharma firm seeks U.S. FDA approval for synthetic secretin product

Rouen University Hospital - Sentinel lymph node detection is enhanced by scintigraphy performed 1 hour postinjection

Royal Free and University of College Medical School, London - Relationship between elevated sPLA₂ IIa levels and CAD risk discovered in diabetes

Ruhr University of Bochum - Catheter ablation resolves regular atrial tachycardia after atrial fibrillation surgery

Rush University Medical Center, Chicago - Melatonin reported successful in shifting the human circadian clock

Rush University Medical Center, Chicago - Recurrent thrombo-embolic events are reduced with Cardia PFO occluder

SUNY, Stony Brook - Myristoylated HIV Gag has greater than 2-fold increase in binding affinity to model rafts

Sage-N Research, Inc. - Launch of web-based protein analysis identification service announced

Salk Institute for Biological Studies - Genetically modified mice become efficient at burning fat

Scripps Research Institute - Scientists re-engineer antibiotic to counter drug resistance

Seoul National University - NaBu proposed as chemopreventive agent for prostate cancer

Sichuan University - Epidermal growth factor receptor induces T cell responses against lung cancer

SkinMedica, Inc. - Benzoyl peroxide prescription acne cream in microsponge delivery system launched

Sonic Innovations, Inc. - Digital hearing aid company reports net sales up 7% in Q4 2005 over a year ago

Sorenson Medical - Chinese FDA approval granted for ambulatory infusion pump for pain management

Spacelabs Healthcare, Inc. - Wireless networking option for compact patient monitors released

St. Jude Children's Hospital, Memphis - Reports add new data to HIV/AIDS vaccines research

St. Jude Children's Research Hospital, Memphis - Efficacy of depsipeptide in childhood cancer models studied

St. Jude Medical, Inc. - U.S. FDA approves new pacemaker platform; company plans immediate U.S. and European launch

St. Thomas' Hospital, London - Effects of phosphodiesterase 5 inhibitors suggest a therapeutic cardiovascular role

Stellenbosch University, Tygerberg - Simple noninvasive methods effectively monitor ingestion of antituberculosis drugs

Stratoxon LLC - Cancer dose-response characteristics of 2,3,7,8-tetrachlorodibenzodioxin studied

Sun Microsystems, Inc. - UCLA Laboratory of Neuro Imaging chooses technology for study of human brains

Sungkyunkwan University School of Medicine, Seoul - Dry pleural dissemination of lung cancer should be diagnosed using CT findings at PET/CT

TREK Diagnostic Systems - Three-year Novation agreement for microbiology blood culture instruments and media signed

Targeted Genetics Corporation - HIV/AIDS vaccine trial launched in Entebbe, Uganda, as three-way collaborative effort

The March of Dimes - Birth defects prevention organization commits additional $2.4 million to research

The Parenteral Drug Association - Education organization and Learnwright partner to deliver education to pharma professionals

Theregen Corporation - Guidant makes equity investment for development of Anginera epicardial patch

Third Military Medical University, Chongqing - Co-transfection into lung cancer cells line can increase chemosensitivity

Thoracic Oncology Research Laboratory, Philadelphia - COX-2 inhibition augments the efficacy of a cancer vaccine

Tm Bioscience - DNA-focused diagnostics company to supply Children's Hospital with genetic test reagents

Tohoku University, Miyagi - Data advance knowledge in prostate cancer research

Tokyo University of Agriculture & Technology - A new I kappa B kinase beta inhibitor prevents human breast cancer progression

Tulane University, New Orleans - Review discusses tools for ischemia imaging and plaque imaging in diabetes

U.S. Centers for Disease Control & Prevention -  Plasmodium vivax was adapted to growth in owl monkeys

U.S. Centers for Disease Control & Prevention - One step, real time RT-PCR assay to detect hepatitis E virus has been developed

U.S. Centers for Disease Control & Prevention - Report describes status of activities to improve immunization delivery

U.S. Department of Health & Human Services - Partnership formed to strengthen pandemic influenza preparedness

U.S. Food & Drug Administration - Article discusses structures of components comprising tripartite multidrug efflux pumps

U.S. National Institutes of Health - Anti-hepatitis C virus antibody quantified in patients with chronic hepatitis C

U.S. National Institutes of Health - Uveitis-associated macular edema was unaffected by vitamin E oral supplementation

U.S. Naval Medical Research Center - Studies advance knowledge in typhus vaccines research

UCB - Developer of antiepileptic drug receives EMEA positive opinion, U.S. FDA approvable letter

Umberto I Hospital, Mestre - Coronary flow reserve offers independent prognostic information in coronary artery disease

Umea University - Women with non hereditary breast cancer more likely to develop breast cancer again

Universidad Nacional Autonoma de Mexico - Review examines risks and benefits of rotavirus vaccines in Latin America

Universidad Nacional de Cordoba - CpG oligodeoxynucleotides function as effective adjuvant in aged mice

Universidade Federal do Rio Grande do Sul, Porto Alegre - Pap test results predict HPV status in young women

University College London - HIV-1 and HIV-2 have different replication kinetics in macrophages

University Hospital Cleveland - BMI appears unrelated to elevated GH and IGF-1 levels in patients with DISH

University Hospital Freiburg - Thermoactive viscoelastic foam pad does not prevent pressure ulcer during heart surgery

University Hospital Mannheim - Endoscopic full-thickness gastric wall resection using flexible stapler shows promise

University Hospital, Birmingham - Inhaled SO₂ reduces cardiac vagal control, may increase risk of ventricular arrhythmia

University Hospital, Frankfurt - Annular compression stitch improves quadrangular resections in mitral valve repair

University Hospital, Munster - Hypoxia is associated with characteristic astrocytic gene expression

University Hospital, Valladolid - Gradient trend confirmed the stable nature of mild aortic stenosis

University of Alberta - Single transmembrane domain IGF-II/M6P receptor activates G-protein, PKC-dependent pathway

University of Arkansas Medical Sciences - Altering TV viewing habits is proposed for adult obesity intervention

University of Barcelona Hospital Clinic-IDIBAPS - Early noninvasive ventilation after extubation reduces risk of respiratory failure

University of Bari - Mixed cryoglobulinemia is characterized by higher hepatitis C virus load

University of Bari - Researchers publish new studies and findings in the area of stem cell transplantation

University of Bristol - Bovine paratuberculosis may not be a cause of Crohn disease

University of California, Los Angeles -  Listeria vaccine elicited central nervous system tumor immunity

University of California, Los Angeles - Ets1-related protein initiates vasculogenesis in zebrafish

University of California, San Diego - Mouse model may aid in drug development for autoimmune and inflammatory disorders

University of California, San Diego - Reports describe recent advances in hemodialysis research

University of Chicago - Findings describe new data in vector development research

University of Cincinnati - Aberrant perforin maturation underlies hemophagocytic lymphohistiocytosis clinical diversity

University of Cologne - Evidence-based guidelines should serve as quality controls in managing testis cancer

University of Edinburgh - PDE5 inhibition does not reverse endothelial dysfunction in coronary artery disease patients

University of Florida - Suspect cytokines do not produce albuminuria in patients with nephrotic syndrome

University of Gdansk - Nonalcoholic fatty liver disease is treatable by gastroplasty

University of Glasgow - Immunohistochemical markers used to identify mesothelioma from serous carcinoma

University of Hamburg - Subthreshold test pulses provide accurate measure of defibrillation lead impedance

University of Heidelberg - Assessment of myocardial perfusion adds value to conventional stress ECG

University of Helsinki - Breaking the cycle of related factors may offer treatment plan for metabolic syndrome

University of Illinois - Bone response to hydroxyapatite scaffolds is visualized

University of Iowa School of Medicine - LIGHT induces ESC differentiation associated with activation of ERK5

University of Michigan - Tiron identified as bortezomib blocker

University of Michigan Health System - Hospitals should stockpile oseltamivir to prepare for avian influenza outbreak

University of Michigan Health System - Minimally invasive procedure works for wide range of aorta problems, study shows

University of Minnesota - EGFRvIII-derived CTL epitopes restricted by HLA A0201 are identified for glioma immunotherapy

University of Minnesota - Technique enables visualization of synchronized interactions of nerve cells in brain

University of Mississippi - Topoisomerase II inhibitors enhanced by using polypeptide inhibitor of c-Myc

University of Navarra - Recent findings in Parkinson disease described

University of New Mexico - Changing patterns of gallbladder carcinoma in New Mexico analyzed

University of Ottawa - Data advance knowledge in cardiovascular research

University of Pisa - Idarubicin displayed cytotoxic effect on breast cancer multicellular spheroids

University of Pittsburgh - Trichostatin A could be used to achieve tumor growth inhibition and cytotoxicity of gliomas

University of Renal Research and Education Association, Ann Arbor - Preemptive transplant for patients with diabetes-related kidney disease benefits some

University of Rochester School of Medicine - Myelinolysis reduced when hyponatremia is rapidly corrected with myoinositol

University of South Carolina - Actical accelerometer is a valid tool for measuring physical activity in children

University of Southern California - Vascular endothelial growth factor messenger RNA may predict liver metastases

University of Stirling - Lower maternal tendencies may be related to higher levels of salivary testosterone

University of Tennessee - Use of cisplatin in metastatic osteosarcoma justified despite toxicity

University of Texas Medical Branch, Galveston - GES induced tachygastria is mediated by an adrenergic pathway and inhibits antral motility

University of Texas Medical Branch, Galveston - Program helps to reach women in remote areas at risk for cervical cancer

University of Texas, Austin - Confocal microscopy could aid detection of cervical precancerous lesions

University of Toronto - Intraislet insulin suppresses glucagon release via GABA-GABA_A receptor system

University of Toronto - More aggressive treatment of Hurthle cell tumors recommended

University of Utah - Oral cephalosporins enhance resistance risk in both treated and untreated individuals

University of Utah - Tumor specific gene delivery is achieved using a pH-responsive system

University of Vienna - Mechanical aortic valve replacement does not affect long-term neurocognitive function

University of Western Australia - Increased physical activity and reduced saturated fat may help maintain mental health

University of the Mediterranean, Marseille - CD146 reflects vascular disturbances in patients with inflammatory bowel disease

Vertex Pharmaceuticals Incorporated - Key studies with hepatitis C therapy successfully completed

Virgen de la Victoria University Hospital, Malaga - High levels of angiogenic protein are linked to the presence of macrophages in breast tumors

Washington University, St. Louis - Iseganan does not prevent ventilator-associated pneumonia during prolonged ventilation

Wayne State University, Detroit - Researchers' work adds to leukemia body of knowledge

Weizmann Institute of Science, Rehovot - New method could substantially speed process of identifying novel protein molecules

Welch Allyn - Spot-check device introduced

William Beaumont Hospital, Royal Oak - Enhanced external counterpulsation benefits are similar among all BMI groups

Wistar Institute, Philadelphia - U.S. FDA licenses vaccine to protect infants against rotavirus infection

Yale University - Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors