Lab Law Weekly

Massachusetts General Hospital - HIV-1 replication capacity is measured by sensitive FACS-based method

Max Delbrueck Centre for Molecular Medicine (MDC) - Physical activity of mice during pregnancy appears to stimulate brain cell growth in offspring

Mayo Clinic & Mayo Foundation - Terascale computing can accelerate development of therapies for SARS and Avian Influenza

Med & Health Research Assoc of New York City, Inc. - Mammography rates underscore important role of healthcare providers

MedImmune Vaccines - Master donor virus for live attenuated influenza vaccines has been genetically mapped

Medeikon Corporation - Medeikon and American Cardiovascular Research Institute collaborate on cardiac disease technology

Medical College of Georgia - Reports advance knowledge in prostate cancer research

Medical College of Wisconsin - Patients with acute myelogenous leukemia should receive consolidation before autotransplantation

Medical University of Vienna - Findings describe new data in atherosclerosis research

Medical University of Vienna - Inflammatory bone destruction requires p38 MAPK activation

Medtronic, Inc. - U.S. FDA approves expanded labeling of Medtronic CRT biventricular pacing systems

Memorial Sloan-Kettering Cancer Center - Prostate cancer diagnosed after repeat biopsies linked to favorable prognosis

Mera Pharmaceuticals - Mera Pharmaceuticals announces first quarter revenue of $152,394

Merck & Co., Inc. - Data analysis shows Vytorin significantly reduced LDL cholesterol in comparison group

Merck & Co., Inc. - Dr. Alan Ezekowitz joins Merck Research Laboratories in key leadership role

Methodist Hospital, Houston - Metastatic thyroid carcinoma restaged in real-time by FDG-PET scanning

Migal Galilee Technology Center - Heat labile Escherichia coli enterotoxin is potential adjuvant for transcutaneous cancer immunotherapy

Mirus Bio Corporation - Mirus Bio announces efficient new genetic immunization method to produce antibodies

Mount Sinai Medical Center, New York - Cervical cancer therapy with total laparoscopic radical hysterectomy appears feasible/safe

Mount Sinai School of Medicine, New York - Breast cancer patients with ATM gene alteration may develop fibrosis after radiotherapy

Myriad Genetics, Inc. - Myriad Genetics' follow-on study of Flurizan demonstrates continued benefit in Alzheimer disease

NOVT Corporation - Novoste sells vascular brachytherapy business to Best Vascular

Nanjing Medical University - 8-iso-PGF_2alpha is linked to coronary artery disease in coronary angiography patients

Nanjing Medical University - Grafted MSCs differentiate into neural cells and improve motor function in ischemic brain

National Center for Genome Resources - Team proposes national tuberculosis archive

National Heart, Lung, & Blood Institute, Framingham - Plasma N-terminal pro-atrial natriuretic peptide is key correlate of vascular endothelial function

Netherlands Institute Brain Research - Neuroanatomical framework for the role of the brain in type 2 diabetes was determined

NitroMed, Inc. - African American heart failure trial shows women, men both benefit from BiDil

NitroMed, Inc. - Clinical response to BiDil evaluated by baseline blood pressure

North Carolina State University - Lymphoma survival predicted by integrated clinical and gene expression data

Norwood Abbey Ltd. - Norwood Abbey signs commercial-phase license agreement with MIT for needle-free injection system

Okayama University of Science - Stilbenoids of Kobresia nepalensis exhibited DNA topoisomerase II inhibition

Osaka City University - Reports add new data to hypertension research

Ottawa Hospital - Quality of life of hepatitis C patients is affected by depression and smoking

Ottawa Hospital - Surveillance programs for stage I nonseminomatous germ cell tumors described

Pacific Biometrics, Inc. - Pacific Biometrics Inc. completes $3.8 million financing

Pharmos Corporation - Pharmos Corporation reports 2005 fourth quarter net loss of $3 million

Pochon CHA University College of Medicine - Researchers' data advance pediatric cardiology research

Pomeranian Medical University, Szczecin - Cytokine gene variants may affect efficacy of immunosuppressive, anti-inflammatory drugs

Praxim Medivision - Praxim Medivision announces plans to enter U.S. market

Professional Education - Cynosure inks agreement for accredited courses for women's health

Progenics Pharmaceuticals, Inc. - Progenics Pharmaceuticals reports fourth quarter revenues were $2 million

Queen's University Belfast, Antrim - Chemotherapy-induced colorectal cancer cell death inhibited by c-FLIP

R.M. Alden Research Laboratory - Intra-abdominal infections treated with moxifloxacin monotherapy

Research Australia - Commission report indicates Australia has benefited from spending on innovation in health care

Roche - New study shows women with osteoporosis prefer treatment in one tablet per month

Royal College of Surgeons in Ireland - Decrease in PI-3K/AKT1 survival signaling mediates DN-HNF-1alpha-induced apoptosis

Royal Free & University College Medical School, London - Postprandial lipemia in diabetics is restored to normal by insulin sensitization with pioglitazone

Sahlgrens University Hospital, Gothenburg - Non-small cell lung cancer treated by stereotactic hypofractionated radiotherapy

Salk Institute for Biological Studies, La Jolla - p/CIP and SRC-1 play key roles in energy balance by controlling energy intake and expenditure

Samaritan Pharmaceuticals, Inc. - Samaritan starts second phase 2 monotherapy trial of oral anti-viral agent in HIV patients

Schering-Plough Corporation - Schering-Plough announces changes in executive finance positions

Sequenom, Inc. - Sequenom launches quantitative methylation and gene expression analysis products

Shanghai Medical University 2 - Research in cancer therapy provides new insights

Simulations Plus, Inc. - Simulations Plus releases upgraded version of modeling software for drug discovery

Sirna Therapeutics, Inc. - Sirna Therapeutics announces members of scientific advisory board

Sisli Erfal Education & Research Hospital, Istanbul - Lisinopril plus telmisartan may prevent diabetic nephropathy type 2 diabetes, hypertension

Songshan Armed Forces Hospital, Taipei - SARS prevention program initiation decreases nursing staff anxiety and depression

Southern Research Institute, Birmingham - Southern Research Institute receives $1.4 million grant to develop anti-viral drug screening tools

St. George's Hospital Medical School, London - Reports describe recent advances in genetics & genomics research

St. John Health - Michigan hospital utilizes Spy Intra-operative Imaging System to confirm success of heart surgery

State University of New York Upstate Medical Center - Leptin has a common link to obesity and hypertension

Stockholm University - ELOVL3 is important for early onset of lipid recruitment in brown adipose tissue

Synthetic Blood International, Inc. - Synthetic Blood enrolls first patient in phase 2 traumatic brain injury study

Taiwan National Defense University - HIV transmission misunderstood by female intravenous drug users in Taiwan

Tel Aviv University - Endogenous factors influence angiogenin production

The Medicines Company - Angiomax monotherapy is superior to heparins plus GP IIb/IIIa combination

Tm Bioscience Corporation - Tm Bioscience licenses P450 pharmacogenetic biomarker from Epidauros Biotechnologie AG

Toho University, Chiba - Diabetic nephropathy progression is delayed by probucol

Tohoku University, Sendai - Tumor angiogenesis is suppressed by oncolytic replication-competent adenovirus

Tokyo Women's Medical University - Bioengineered grafts generate angiogenesis

Toshiba America Medical Systems Inc. - U.S. FDA grants clearance for Toshiba's MRI system with advanced cardiac imaging applications

U.K. Health Protection Agency Center for Infections, London -  Acinetobacter species-expressing bla(OXA-58) carbapenemases geographically widespread

U.S. Centers for Disease Control & Prevention - Researchers' work adds to HIV/AIDS therapy body of knowledge

U.S. National Cancer Institute - Breast cancer angiogenesis yields to bevacizumab

U.S. National Cancer Institute - Dendritic cell activation by HPV-16 vaccine involves a specific C-type lectin

U.S. National Cancer Institute - Predicting posttraumatic growth in breast cancer survivors discussed

U.S. National Institute of Child Health & Human Development - Fat distribution pattern and coronary risk profile linked to X chromosome

U.S. National Institute of Mental Health - Gene influences antidepressant response

U.S. National Institutes of Health - Chondrogenesis occurs in a diminished capacity in mesenchymal SC-laden hydrogels

U.S. National Institutes of Health - Stem cell transplant survival in CML associated with higher 30-day lymphocyte count

Universite de Caen - A new streptogramin was bactericidal until target strains acquired an erm gene

University Clinic of Munich - Carotid endarterectomy is associated with transient increase in S-100B serum levels

University Clinic, Essen - Recent studies add new data to statins research

University Hospital Birmingham NHS Trust - Transplant-related mortality increased in non-Caucasians undergoing standard sibling SCT

University Hospital of Geneva - ATM gene promoter analysis of childhood lymphoid malignancies conducted

University at Buffalo - Reports advance knowledge in breast cancer research

University of Alabama - Total abdominal liposuction followed by abdominoplasty is proposed for massive weight loss

University of Alberta - Rapid Ca²⁺ uptake by SERCA pump controls insulin secretion amount

University of Amsterdam - Genetic mutations associated with azathioprine toxicity do not predict hepatoxicity

University of Arkansas for Medical Sciences - Early multiple myeloma treatment failure is initiated by synergy between cyclin D2 and CKS1B

University of Barcelona - Researchers report details of new studies and findings in the area of hepatitis B virus

University of California, Los Angeles - Lung cancer cannot be staged adequately by PET/CT of the chest during shallow breathing

University of California, San Francisco - Neutrophil chemotaxis requires Hem-1 complexes

University of California, San Francisco - Studies describe new findings in hepatocellular cancer research

University of Cardiff Wales - Endosomes and lysosomes are the receptors for peptide localization

University of Chicago - Botulinum toxin type A may be a therapy for interstitial cystitis or sensory urgency

University of Florida - Low-carbohydrate, high-protein diets improve body mass/composition regardless of energy intake

University of Glasgow - Atherosclerotic events are reduced as effectively by angiotensin receptor blockers as ACE inhibitors

University of Hong Kong - HCC proteomic profiling reveals heat-shock protein up-regulation

University of Illinois - Estrogen induction protects cells from mediated apoptosis

University of Illinois - University of Illiniois chemists devise method makes ligation reactions permanent

University of Laval, Sainte Foy - Proteins with whey-acidic-protein (WAP) motifs implicated in carcinogenesis

University of Leipzig - Severe infectious tuberculosis in childhood may become epidemiologically important

University of Lund Hospital - Acute myeloid leukemia linked to cyclin A1 expression

University of Manitoba - Hepatitis C virus clinic treatment outcomes are comparable with clinical trials

University of Massachusetts - RNA interference-based screen identifies MAP4K4/NIK as a negative regulator

University of Melbourne - Retinopathy signs plus a family history of diabetes predict subsequent diabetes risk

University of Michigan - Bladder cancer mortality in the U.S. influenced by gender and geography

University of Munich - Uronic acid functionalized copolymers can be synthetic gene carriers

University of Munster - Chronic pelvic pain may correlate to COX-2 overexpression in peritoneal lesions

University of Munster - Effects of HDL-associated lysosphingolipids operate via Akt->NF-kappa B signaling pathways

University of Newcastle upon Tyne - Insulin aspart was well tolerated and effective during long-term type 1 diabetes treatment

University of Oklahoma - Hypertension and cardiovascular disease risk are linked to age, diabetes, and albuminuria

University of Oxford - Analysis of cancer prevention strategies for gastrointestinal cancer conducted

University of Oxford - Hypoglycemic medication beliefs among type 2 diabetes mediates success rate

University of Piemonte Orientale Amedeo Avogadro - Ghrelin secretion is lower in obese, but responds equally to oral glucose in obese and lean

University of Pittsburgh - Advanced heart failure is independent predictor of inappropriate ICD shocks

University of Pittsburgh Medical Center - Resected non-small cell lung cancer linked to extreme chemotherapy resistance

University of Rochester Medical Center - IFN-gamma alone may be insufficient to evaluate breadth of HIV-specific T cell response

University of Sao Paulo - Scintigraphy utilizing Tc-99m is an effective method to assess improvement in gastric function

University of Sao Paulo Medical School - Findings in cardiovascular disease provide new insights

University of South Florida - Cardiac migraine may be a distinct entity

University of St. Andrews - Colon cancer targeting of parvoviruses is achieved by insertion in P4 promoter

University of Texas, Austin - Integrated treatment of psychiatric and substance use disorders is cost effective

University of Tokyo Graduate School of Medicine - Multiple epitope-specific CTL responses control immunodeficiency virus replication

University of Toronto - Researchers devise way to unravel DNA tangles, offering possibilities for cancer treatment

University of Turin - Hepatocellular carcinoma treated by radiofrequency thermal ablation

University of Uppsala - Individualized therapy improved bulimia treatment

University of Washington - Pausing during reverse transcription increases the rate of retroviral recombination

University of Washington - Recent findings in biomedical engineering described

University of Zagreb - Studies add new findings to diet & nutrition body of knowledge

Uppsala University - New findings in the area of diabetes pathogenesis detailed

Vanderbilt University, Nashville - Nodal gene expression and signaling is cooperatively and autonomously regulated in Xenopus

Verus Pharmaceuticals, Inc. - Verus donates 5,000 epinephrine auto-injector demonstrators for Anaphylaxis Day at meeting

Virginia Commonwealth University - Risk of lower back pain may be increased in women with past gynecological surgeries

Washington University, St. Louis - Duloxetine offers diabetic neuropathy treatment

Westpfalz-Klinikum Kaiserslautern - Sleep-related breathing disorder therapies must be determined individually

William Harvey Research Institute, London - Homocysteine-induced endothelin-1 release depends on hyperglycemia and reactive oxygen species

XOMA Ltd. - XOMA reports total 2005 revenues of $18.7 million, up from $3.7 million in 2004

Yalgado Ouedraogo University Health Center, Ouagadougou - Tuberculosis diagnosis delay due to lack of patient education and health worker incompetence

iCo Therapeutics Inc. - Renowned retinal specialist Alan Bird joins iCO Therapeutics' strategic advisory team

invivodata inc. - Invivodata integrates devices for patient-reported data recording in clinical trial