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Max Planck Institute for Infection Biology, Berlin

Vaccine prevents Helicobacter pylori-induced alterations of gastric flora

Published in Lab Law Weekly, April 28th, 2006

Vaccination prevents Helicobacter pylori-induced alterations of the gastric flora in mice.

"Molecular analysis of the gastric microflora in mice revealed that Helicobacter pylori infection causes an increase in microbial diversity. The stomachs of H. pylori-infected animals were colonized by bacteria which are naturally restricted to the lower intestinal tract," researchers in Germany report.

"Clostridia, Bacteroides/Prevotella species, Eubacterium species, Ruminococcus species, streptococci, and Escherichia coli were detected exclusively in the stomachs of infected animals, whereas lactobacilli...

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