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Biodefense

Aeolus Pharmaceuticals' AEOL 10150 Protects Lungs Against Mustard Gas

Published in Lab Law Weekly, November 23rd, 2007

Aeolus Pharmaceuticals, Inc. (OTCBB:AOLS), announced that researchers from National Jewish Medical & Research Center have reported that Aeolus' lead compound, AEOL 10150 showed statistically significant protection of lung tissue in animals exposed to 2-chloroethyl-ethylsulfide (CEES; half-mustard). In a study sponsored by the National Institutes of Health ("NIH") CounterACT program, AEOL 10150 was tested along with 19 other compounds to determine effectiveness in protecting lung tissue against edema and hemorrhage resulting from exposure to mustard gas.

AEOL 10150 was given to rats one hour after CEES exposure and again 6 hours later. Eighteen hours after exposure, lung...

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