Life Sciences
Findings from Alkermes, Inc. provide new insights into life sciences
Published in Lab Law Weekly, June 27th, 2008
Scientists discuss in 'Overriding the blockade of antinociceptive actions of opioids in rats treated with extended-release naltrexone' new findings in life sciences. According to recent research from the United States, "A monthly extended-release formulation of the opioid antagonist naltrexone (XR-NTX) is approved for treatment of alcohol dependence. There is little research regarding overriding chronic (>21 days) competitive opioid receptor blockade with opioids for acute pain."
"Using the hot plate test after XR-NTX or placebo microsphere administration, rats were treated with an opioid analgesic to determine the dose required to produce the maximum response...
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Source: Lab Law Weekly (2008-06-27)
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