Controlled Release
Research from Ajinomoto Co., Inc. in the area of controlled release described
Published in Lab Law Weekly, October 30th, 2009
According to recent research from Kawasaki, Japan, "We designed a single unit type tablet formulation containing nateglinide to decrease both postprandial blood glucose level (PBG) and fasting blood glucose level (FBG) in normal beagle dogs. The tablet was a dry coated tablet comprising both a core tablet (an erosion matrix tablet: a controlled release portion(nateglinide: 90 mg)) and an outer shell (an immediate release portion (nateglinide: 60 mg))."
"The weight, the diameter and the hardness of the obtained tablet were 416.1 mg, 10 mm phi, about 60 N, respectively. The dissolution study of the obtained tablet in pH 1.2 or 6.8 showed that the nateglinide in the...
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Source: Lab Law Weekly (2009-10-30)
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