Chiba University

Adult cardiac Sca-1+ cells have stem-cell potential

Published in Law and Health Weekly, May 8th, 2004

Adult cardiac cells expressing Sca-1 have stem-cell potential in mice.

"Although somatic stem cells have been reported to exist in various adult organs, there have been few reports concerning stem cells in the heart," scientists in Japan noted.

In a recent study, K. Matsuura and coauthors at Chiba University found that "Sca-1-positive (Sca-1+) cells in adult hearts have some of the features of stem cells.

"Sca-1+ cells were isolated from adult murine hearts by a magnetic cell sorting system and cultured on gelatin-coated dishes," they explained. "A fraction of Sca-1+ cells stuck to the culture dish and proliferated slowly. When...

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Source: Law and Health Weekly (2004-05-08)

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