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Stanford University

Transplant rejection averted by simple light exposure in Stanford animal study

Published in Law and Health Weekly, May 29th, 2004

One of the unfortunate side effects of bone marrow and stem cell transplantation is that the newly implanted cells often stage an internal attack against the patient they're intended to help.

Stanford University School of Medicine researchers now have a better grasp of this phenomenon, known as graft-vs.-host disease, or GVHD, and have proposed a possible method of prevention: simple ultraviolet light.

In a new animal study, researchers identified the principal culprit in GVHD: an immune cell in the skin known as a Langerhans cell. These cells normally function as flag posts for the immune system, signaling infection-fighting T cells to come to a...

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