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Law & Health Weekly

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Breast Cancer



Increased false-negative rates reported with new breast cancer staging system



June 26th, 2004

The revised classification system for axillary sentinel lymph nodes defined in the sixth edition of the American Joint Committee on Cancer (AJCC) staging system for breast cancer led to higher false-negative diagnosis rates in a study from Canada.

The latest edition of the AJCC staging system for breast cancer now defines axillary sentinel lymph nodes with micrometastatic deposits 0.2 mm in diameter or smaller as node-negative.

David R. McCready, MD, MSc, of the University of Toronto, and colleagues explored how the revision affected sentinel lymph node positivity, the false-negative rate, and the overall accuracy of the sentinel lymph node biopsy in...


Source: Law & Health Weekly (2004-06-26)

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