Sungkyunkwan University, Seoul

Initial bone marrow involvement is infrequent in nasal-type NK/T cell lymphoma

Published in Law and Health Weekly, June 26th, 2004

EBV in situ hybridization (ISH) is helpful in diagnosing nasal lymphoma, researchers say.

According to a study from South Korea, "To evaluate the frequency of bone marrow involvement by nasal-type NK/T cell lymphoma, we retrospectively studied biopsy specimens from 40 patients by EBV ISH. Three patients had marrow involvement at initial diagnosis (7.5%)."

"In one patient (1/40, 2.5%), the disease in bone marrow was recognized by routine morphological assessment, while two other patients had minimal involvement of lymphoma cells which was recognized only by EBV ISH (2/40, 5%). Two patients had a disseminated disease at diagnosis and died 6 days and...

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Source: Law and Health Weekly (2004-06-26)

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