Kyoto University

Protein's potential anti-apoptotic function may play role in fibroid growth

Published in Law and Health Weekly, November 27th, 2004

A study from Japan found that a member of the S100 protein family appears to have anti-apoptotic activity, and play a role in the growth of uterine leiomyomas, or fibroids.

"S100 proteins belong to the EF-hand Ca²⁺ -binding protein family and regulate a variety of cellular processes via interaction with different target proteins. Several diseases, including cancer and melanoma, are related to the abnormal expression of S100 proteins, which are expressed in cell- and tissue-specific manners," said T. Kanamori and colleagues, Kyoto University.

When these researchers studied the expression of S100 proteins in human uterine smooth muscle...

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Source: Law and Health Weekly (2004-11-27)

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