Emory University
IL-15 is superior to IL-2 in generating of long-lived memory T cells
Published in Law and Health Weekly, November 27th, 2004
"Using tetanus toxoid (TT) and influenza (Flu) immunization of rhesus macaques as a model, the effect of IL-2 and IL-15 on the generation and maintenance of antigen specific memory T cells was evaluated following primary and secondary immunization. Daily cytokine administration expanded primarily effector but not memory cells, while spacing cytokine administration to q3-7 days markedly enhanced TT and Flu specific memory responses," researchers in the United States report.
"Following primary immunization, TT specific CD4 and...
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