Grantham Hospital, U.K.

Risk factors for early relapse of tuberculosis described

Published in Law and Health Weekly, December 11th, 2004

In a large study of tuberculosis patients, researchers found that disease relapse was associated with a thrice weekly vs. a daily drug therapy regimen and with the presence of cavitation (cavities) on the individual's chest X-ray at diagnosis.

Researchers at Grantham Hospital, Grantham, U.K., studied 12,183 patients who completed antituberculosis treatment between January 1, 1998, and December 31, 2000. Of this group, more than 105 cases relapsed within 30 months after commencement of treatment. The mean time to relapse was almost 15 months. A group of 166 controls completed 30 months of follow-up at clinics. Of those who took the standard 6-month therapy of isoniazid...

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Source: Law and Health Weekly (2004-12-11)

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