Hirosaki University
CYP2C19 genotype determines extent of fluvoxamine/lansoprazole interaction
Published in Law and Health Weekly, January 1st, 2005
"Lansoprazole is a substrate of CYP2C19 and CYP3A4," scientists in Japan explained.
N. Yasui-Furukori and colleagues at Hirosaki University conducted a study "to compare the inhibitory effects of fluvoxamine, an inhibitor of CYP2C19, on the metabolism of lansoprazole between CYP2C19 genotypes."
"Eighteen volunteers -- of whom six were homozygous extensive metabolizers (EMs), six were heterozygous EMs, and six were poor metabolizers (PMs) for CYP2C19 -- received three 6-day courses of either daily 50 mg fluvoxamine or placebo in a...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Law and Health Weekly
More Articles from Law and Health Weekly
- Biotechnology Industry Organization
Biotech group urges Congress to keep patent fees at PTO - Institute of Immunology, Zagreb
Assay to measure Fc function of immunoglobulin preparations developed - Intarcia Therapeutics Inc.
Pharmaceutical company announces new appointments to board of directors - Legal Issues
Merck appoints committee to review company actions on Vioxx - Medical Ethics
New center to study medical ethics in the care of children - Medicare
Drug card enrollment falls short - More from this issue of Law and Health Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
